STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ60760.1Protein of unknown function UPF0047; PFAM: Uncharacterised protein family UPF0047; TIGRFAM: secondary thiamine-phosphate synthase enzyme; COGs: COG0432 conserved hypothetical protein; InterPro IPR001602; KEGG: sta:STHERM_c18030 automatic annotation; PFAM: Uncharacterised protein family UPF0047; SPTR: Putative uncharacterized protein; TIGRFAM: Uncharacterised protein family UPF0047. (149 aa)    
Predicted Functional Partners:
AEJ60761.1
PFAM: Histone deacetylase domain; COGs: COG0123 Deacetylase including yeast histone deacetylase and acetoin utilization protein; InterPro IPR000286; KEGG: sta:STHERM_c18020 histone deacetylase superfamily; PFAM: Histone deacetylase superfamily; SPTR: Histone deacetylase superfamily.
       0.782
AEJ60759.1
PFAM: ROK family; COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: sta:STHERM_c18040 hypothetical protein; PFAM: ROK; SPTR: Fructokinase.
       0.705
AEJ60758.1
PFAM: Metallopeptidase family M24; Creatinase/Prolidase N-terminal domain; COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR000587:IPR000994; KEGG: sta:STHERM_c18050 hypothetical protein; PFAM: Peptidase M24, structural domain; Creatinase; SPTR: Peptidase M24.
       0.508
AEJ60762.1
PFAM: Bacterial extracellular solute-binding protein; COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: dtu:Dtur_1732 extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding, family 1; SPTR: Carbohydrate ABC transporter substrate-binding protein, CUT1 family.
       0.416
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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