STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEJ60765.1Transcriptional regulator, CopG family; TIGRFAM: putative iron-only hydrogenase system regulator; KEGG: sta:STHERM_c18010 transcriptional regulator, CopG family; SPTR: Putative uncharacterized protein. (83 aa)    
Predicted Functional Partners:
AEJ60767.1
PFAM: Radical SAM superfamily; TIGRFAM: iron-only hydrogenase maturation rSAM protein HydE; COGs: COG0502 Biotin synthase; InterPro IPR006638:IPR007197; KEGG: sta:STHERM_c17990 hypothetical protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein.
 
    0.932
AEJ60766.1
PFAM: Radical SAM superfamily; Biotin and Thiamin Synthesis associated domain; TIGRFAM: iron-only hydrogenase maturation rSAM protein HydG; thiazole biosynthesis protein ThiH; COGs: COG1060 Thiamine biosynthesis protein ThiH; InterPro IPR007197:IPR010722; KEGG: sta:STHERM_c18000 hypothetical protein; PFAM: Biotin/thiamin synthesis-associated protein; Radical SAM; SPTR: Iron-only hydrogenase maturation protein HydG.
 
     0.919
AEJ62407.1
ABC-type transporter, integral membrane subunit; PFAM: FecCD transport family; COGs: COG0609 ABC-type Fe3+-siderophore transport system permease component; InterPro IPR000522; KEGG: sta:STHERM_c21070 transporter; PFAM: Bacterial transport system permease protein; SPTR: Transport system permease protein.
  
 
 0.913
AEJ60769.1
Small GTP-binding protein; PFAM: GTPase of unknown function; TIGRFAM: hydrogenase maturation GTPase HydF; small GTP-binding protein domain; COGs: COG1160 GTPase; InterPro IPR005225:IPR002917; KEGG: sta:STHERM_c17970 hypothetical protein; PFAM: GTP-binding protein, HSR1-related; SPTR: Small GTP-binding protein; TIGRFAM: Small GTP-binding protein.
 
    0.897
AEJ62408.1
PFAM: Periplasmic binding protein; COGs: COG0614 ABC-type Fe3+-hydroxamate transport system periplasmic component; InterPro IPR002491; KEGG: sta:STHERM_c21080 hypothetical protein; PFAM: Periplasmic binding protein; SPTR: Periplasmic binding protein.
  
 
 0.853
AEJ60768.1
PFAM: Lyase; COGs: COG1027 Aspartate ammonia-lyase; InterPro IPR000362; KEGG: sta:STHERM_c17980 aspartate ammonia-lyase AspA; PFAM: Fumarate lyase; SPTR: Fumarate lyase.
       0.721
AEJ61770.1
Hydrogenase, Fe-only; PFAM: 2Fe-2S iron-sulfur cluster binding domain; Iron only hydrogenase large subunit, C-terminal domain; NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Iron hydrogenase small subunit; TIGRFAM: hydrogenase, Fe-only; COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterProIPR001041:IPR019574:IPR001450:IPR004108:IPR 003149:IPR013352; KEGG: sta:STHERM_c13740 hypothetical protein; PFAM: Iron hydrogenase, large subunit, C-terminal; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; Ferredoxin; 4Fe-4S ferredoxin, iron-sulp [...]
 
     0.483
AEJ60920.1
Hydrogenase, Fe-only; PFAM: 2Fe-2S iron-sulfur cluster binding domain; Iron only hydrogenase large subunit, C-terminal domain; NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Iron hydrogenase small subunit; TIGRFAM: hydrogenase, Fe-only; COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterProIPR013352:IPR001041:IPR019574:IPR001450:IPR 004108:IPR003149; KEGG: sta:STHERM_c06260 hypothetical protein; PFAM: Iron hydrogenase, large subunit, C-terminal; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; Ferredoxin; 4Fe-4S ferredoxin, iron-sulp [...]
 
     0.470
AEJ61539.1
Fe-S cluster domain protein; PFAM: Iron only hydrogenase large subunit, C-terminal domain; Putative Fe-S cluster; COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterPro IPR001450:IPR007202; KEGG: sta:STHERM_c12360 hypothetical protein; PFAM: Putative Fe-S cluster; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: Fe-S cluster domain protein.
 
     0.465
AEJ60763.1
ABC-type transporter, integral membrane subunit; PFAM: Binding-protein-dependent transport system inner membrane component; COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: dtu:Dtur_1731 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Carbohydrate ABC transporter membrane protein 1, CUT1 family.
       0.448
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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