STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ60780.1Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the BPG-independent phosphoglycerate mutase family. (553 aa)    
Predicted Functional Partners:
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
 
 0.990
pgk
PFAM: Phosphoglycerate kinase; COGs: COG0126 3-phosphoglycerate kinase; HAMAP: Phosphoglycerate kinase; InterPro IPR001576; KEGG: sta:STHERM_c09800 phosphoglycerate kinase; PFAM: Phosphoglycerate kinase; SPTR: Phosphoglycerate kinase.
  
 
 0.986
AEJ60424.1
PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; COGs: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenase; InterPro IPR006139:IPR006140:IPR002912; KEGG: sta:STHERM_c01490 hypothetical protein; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; Amino acid-binding ACT; SPTR: D-3-phosphoglycerate dehydrogenase.
    
 0.904
AEJ60674.1
PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; COGs: COG1052 Lactate dehydrogenase and related dehydrogenase; InterPro IPR006139:IPR006140; KEGG: sta:STHERM_c04240 hypothetical protein; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; SPTR: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding.
    
 0.904
AEJ62291.1
MOFRL domain protein; PFAM: MOFRL family; COGs: COG2379 Putative glycerate kinase; InterPro IPR007835; KEGG: sta:STHERM_c19830 hypothetical protein; PFAM: MOFRL; SPTR: Hydroxypyruvate reductase.
    
  0.902
pgi
PFAM: Phosphoglucose isomerase; COGs: COG0166 Glucose-6-phosphate isomerase; HAMAP: Phosphoglucose isomerase (PGI); InterPro IPR001672; KEGG: sta:STHERM_c20070 glucose-6-phosphate isomerase; PFAM: Phosphoglucose isomerase (PGI); SPTR: Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 
 0.882
AEJ61645.1
PFAM: Fructose-bisphosphate aldolase class-II; TIGRFAM: ketose-bisphosphate aldolases; fructose-1,6-bisphosphate aldolase, class II, various bacterial and amitochondriate protist; COGs: COG0191 Fructose/tagatose bisphosphate aldolase; InterPro IPR000771:IPR011289; KEGG: sta:STHERM_c07850 fructose-bisphosphate aldolase; PFAM: Ketose-bisphosphate aldolase, class-II; SPTR: Fructose-bisphosphate aldolase; TIGRFAM: Fructose-1,6-bisphosphate aldolase, class II; Ketose-bisphosphate aldolase, class-II.
   
 
 0.858
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 
 0.848
zwf
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
   
 
 0.846
AEJ60409.1
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 
 0.842
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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