STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEJ60831.1PFAM: Bacterial SH3 domain; InterPro IPR013247; KEGG: sta:STHERM_c05290 hypothetical protein; PFAM: SH3, type 3; SPTR: SH3 type 3 domain protein. (117 aa)    
Predicted Functional Partners:
uvrB
UvrABC system protein B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and [...]
       0.773
AEJ60829.1
Peptidase S1 and S6 chymotrypsin/Hap; PFAM: Trypsin; COGs: COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain; InterPro IPR001478:IPR001254; KEGG: sta:STHERM_c05270 hypothetical protein; PFAM: Peptidase S1/S6, chymotrypsin/Hap; SMART: PDZ/DHR/GLGF; SPTR: DegP2 peptidase.
       0.768
AEJ60828.1
PFAM: Magnesium chelatase, subunit ChlI; Lon protease (S16) C-terminal proteolytic domain; TIGRFAM: Mg chelatase-related protein; COGs: COG0606 ATPase with chaperone activity; InterPro IPR004482:IPR003593:IPR000523; KEGG: sta:STHERM_c05260 hypothetical protein; PFAM: Magnesium chelatase, ChlI subunit; SMART: ATPase, AAA+ type, core; SPTR: Mg chelatase, subunit ChlI; TIGRFAM: Mg chelatase-related protein.
       0.572
AEJ60832.1
TIGRFAM: phosphate binding protein; COGs: COG0226 ABC-type phosphate transport system periplasmic component; InterPro IPR011862; KEGG: sta:STHERM_c05300 phosphate ABC transporter phosphate-binding protein; SPTR: Phosphate ABC transporter substrate-binding protein, PhoT family; TIGRFAM: Phosphate binding protein.
       0.548
AEJ60825.1
KEGG: sta:STHERM_c05230 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.474
AEJ60826.1
Methyltransferase type 11; PFAM: Methyltransferase domain; InterPro IPR013216; KEGG: sta:STHERM_c05240 SAM-dependent methyltransferase; PFAM: Methyltransferase type 11; SPTR: Methyltransferase type 11.
       0.474
rnhA
Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
       0.474
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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