Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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gene co-occurrence
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AEJ60834.1PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: phosphate ABC transporter, permease protein PstA; COGs: COG0581 ABC-type phosphate transport system permease component; InterPro IPR005672:IPR000515; KEGG: sta:STHERM_c05320 transporter; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Phosphate ABC transporter membrane protein 2, PhoT family; TIGRFAM: Phosphate transport system permease protein 2. (300 aa)    
Predicted Functional Partners:
AEJ60832.1
TIGRFAM: phosphate binding protein; COGs: COG0226 ABC-type phosphate transport system periplasmic component; InterPro IPR011862; KEGG: sta:STHERM_c05300 phosphate ABC transporter phosphate-binding protein; SPTR: Phosphate ABC transporter substrate-binding protein, PhoT family; TIGRFAM: Phosphate binding protein.
 
 0.999
AEJ60833.1
Phosphate ABC transporter, inner membrane subunit PstC; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
 
0.999
pstB
Phosphate ABC transporter, ATPase subunit; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
 
 0.999
AEJ60840.1
Phosphate uptake regulator, PhoU; Plays a role in the regulation of phosphate uptake.
 
  
 0.983
AEJ60836.1
KEGG: sta:STHERM_c05340 hypothetical protein; SPTR: Glyoxalase/bleomycin resistance protein/dioxygenase.
       0.496
AEJ61321.1
PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II; COGs: COG0069 Glutamate synthase domain 2; InterPro IPR000583:IPR006982:IPR002932:IPR002489; KEGG: sta:STHERM_c10240 glutamate synthase; PFAM: Glutamate synthase, central-C; Glutamine amidotransferase, class-II; Glutamate synthase, central-N; Glutamate synthase, alpha subunit, C-terminal; SPTR: Glutamate synthase (NADH) large subunit.
     
 0.430
AEJ61531.1
PFAM: Alkaline phosphatase; COGs: COG1785 Alkaline phosphatase; InterPro IPR001952; KEGG: sta:STHERM_c12290 alkaline phosphatase; PFAM: Alkaline phosphatase; SMART: Alkaline phosphatase; SPTR: Alkaline phosphatase.
  
  
 0.423
uvrB
UvrABC system protein B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and [...]
       0.413
AEJ60829.1
Peptidase S1 and S6 chymotrypsin/Hap; PFAM: Trypsin; COGs: COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain; InterPro IPR001478:IPR001254; KEGG: sta:STHERM_c05270 hypothetical protein; PFAM: Peptidase S1/S6, chymotrypsin/Hap; SMART: PDZ/DHR/GLGF; SPTR: DegP2 peptidase.
     
 0.410
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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