STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
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[Homology]
Score
pstBPhosphate ABC transporter, ATPase subunit; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. (278 aa)    
Predicted Functional Partners:
AEJ60833.1
Phosphate ABC transporter, inner membrane subunit PstC; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
 
 
 0.999
AEJ60834.1
PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: phosphate ABC transporter, permease protein PstA; COGs: COG0581 ABC-type phosphate transport system permease component; InterPro IPR005672:IPR000515; KEGG: sta:STHERM_c05320 transporter; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Phosphate ABC transporter membrane protein 2, PhoT family; TIGRFAM: Phosphate transport system permease protein 2.
 
 
 0.999
AEJ60832.1
TIGRFAM: phosphate binding protein; COGs: COG0226 ABC-type phosphate transport system periplasmic component; InterPro IPR011862; KEGG: sta:STHERM_c05300 phosphate ABC transporter phosphate-binding protein; SPTR: Phosphate ABC transporter substrate-binding protein, PhoT family; TIGRFAM: Phosphate binding protein.
 
 
 0.997
AEJ60840.1
Phosphate uptake regulator, PhoU; Plays a role in the regulation of phosphate uptake.
 
  
 0.981
AEJ60899.1
PFAM: ABC transporter; ABC transporter transmembrane region; COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterPro IPR001140:IPR003439:IPR003593; KEGG: sta:STHERM_c06050 transporter; PFAM: ABC transporter-like; ABC transporter, transmembrane region; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein.
 
     
0.898
AEJ60836.1
KEGG: sta:STHERM_c05340 hypothetical protein; SPTR: Glyoxalase/bleomycin resistance protein/dioxygenase.
       0.499
AEJ61531.1
PFAM: Alkaline phosphatase; COGs: COG1785 Alkaline phosphatase; InterPro IPR001952; KEGG: sta:STHERM_c12290 alkaline phosphatase; PFAM: Alkaline phosphatase; SMART: Alkaline phosphatase; SPTR: Alkaline phosphatase.
  
  
 0.461
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
 
   
 0.444
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
   
 
 0.425
uvrB
UvrABC system protein B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and [...]
  
    0.405
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.