STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ60845.1Signal transduction histidine kinase, nitrogen specific, NtrB; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG3852 Signal transduction histidine kinase nitrogen specific; InterPro IPR000014:IPR003661:IPR003594:IPR013656; KEGG: sta:STHERM_c05430 sensory transduction histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS fold-4; SMART: ATP-binding region, ATPase-like; Signal transduction histidine [...] (388 aa)    
Predicted Functional Partners:
AEJ60846.1
Two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: Response regulator receiver domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789:IPR003593:IPR002078:IPR002197; KEGG: sta:STHERM_c05440 transcriptional regulatory protein; PFAM: RNA polymerase sigma factor 54, interaction; Signal transduction response regulator, receiver region; Helix-turn-helix, Fis-type; SMART: Signal transduction response regulator, receiver r [...]
 
 0.951
AEJ62300.1
PFAM: Response regulator receiver domain; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789; KEGG: sta:STHERM_c19930 transcriptional regulatory protein; PFAM: Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region; SPTR: Response regulator receiver protein.
 
 
 
 0.866
AEJ60839.1
Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: sta:STHERM_c05370 transcriptional regulatory protein; PFAM: Signal transduction response regulator, receiver region; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver region; SPTR: Two component transcriptional regulator, winged he [...]
 
 
 0.829
AEJ60863.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR001789:IPR003594; KEGG: sta:STHERM_c05630 two-component regulatory system response regulator; PFAM: Signal transduction response regulator, receiver region; ATP-binding region, ATPase-like; SMART: Signal transduction response regulator, receiver region; SPTR: Response regulator receiver sensor signal transduction histidine kinase.
 
 
 0.829
AEJ60844.1
COGs: COG2812 DNA polymerase III gamma/tau subunits; KEGG: sta:STHERM_c05420 DNA polymerase III domain-containing protein; SPTR: Putative uncharacterized protein.
       0.800
AEJ61089.1
PFAM: Response regulator receiver domain; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: sta:STHERM_c14180 response regulator; PFAM: Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region; SPTR: Response regulator receiver protein.
 
 
 0.794
murG
Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.
       0.792
AEJ60843.1
PFAM: Colicin V production protein; InterPro IPR003825; KEGG: sta:STHERM_c05410 hypothetical protein; PFAM: Colicin V production protein; SPTR: Colicin V production protein.
       0.789
AEJ60624.1
PFAM: Response regulator receiver domain; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: sta:STHERM_c03710 response regulator receiver protein; PFAM: Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region; SPTR: Response regulator receiver protein.
 
 
 
 0.786
AEJ61109.1
PFAM: Nitrogen regulatory protein P-II; COGs: COG0347 Nitrogen regulatory protein PII; InterPro IPR002187; KEGG: sta:STHERM_c13230 transcriptional regulatory protein; PFAM: Nitrogen regulatory protein PII; SPTR: Nitrogen regulatory protein P-II.
  
 
 0.782
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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