STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ60855.1PFAM: Endonuclease/Exonuclease/phosphatase family; COGs: COG3568 Metal-dependent hydrolase; InterPro IPR005135; KEGG: sta:STHERM_c05550 endonuclease/exonuclease/phosphatase family protein; PFAM: Endonuclease/exonuclease/phosphatase; SPTR: Endonuclease/exonuclease/phosphatase. (311 aa)    
Predicted Functional Partners:
clpP
ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
       0.789
AEJ60874.1
Cysteine desulfurase, SufS subfamily; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
    
   0.737
AEJ60856.1
KEGG: sta:STHERM_c05560 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.631
AEJ60544.1
PFAM: Uncharacterised protein family (UPF0158); KEGG: sta:STHERM_c02740 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.592
era
GTP-binding protein Era-like-protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
       0.562
AEJ62522.1
Glycoside hydrolase family 37; PFAM: Trehalase; COGs: COG1626 Neutral trehalase; InterPro IPR001661; KEGG: sta:STHERM_c22220 hypothetical protein; PFAM: Glycoside hydrolase, family 37; SPTR: Glycoside hydrolase family 37.
  
    0.557
AEJ60843.1
PFAM: Colicin V production protein; InterPro IPR003825; KEGG: sta:STHERM_c05410 hypothetical protein; PFAM: Colicin V production protein; SPTR: Colicin V production protein.
 
    0.545
AEJ61456.1
PpiC-type peptidyl-prolyl cis-trans isomerase; PFAM: PPIC-type PPIASE domain; InterPro IPR000297; KEGG: sta:STHERM_c11500 hypothetical protein; PFAM: Peptidyl-prolyl cis-trans isomerase, PpiC-type; SPTR: PpiC-type peptidyl-prolyl cis-trans isomerase.
  
     0.497
AEJ60857.1
PFAM: Xylose isomerase-like TIM barrel; COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307; KEGG: sta:STHERM_c05570 xylose isomerase domain-containing protein; PFAM: Xylose isomerase, TIM barrel domain; SPTR: Xylose isomerase domain-containing protein TIM barrel.
       0.476
AEJ62503.1
PFAM: DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit; COGs: COG1466 DNA polymerase III delta subunit; InterPro IPR005790:IPR010372; KEGG: sta:STHERM_c22020 hypothetical protein; PFAM: DNA polymerase III, delta; SPTR: DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit.
  
     0.474
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.