Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEJ60857.1PFAM: Xylose isomerase-like TIM barrel; COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307; KEGG: sta:STHERM_c05570 xylose isomerase domain-containing protein; PFAM: Xylose isomerase, TIM barrel domain; SPTR: Xylose isomerase domain-containing protein TIM barrel. (276 aa)    
Predicted Functional Partners:
AEJ60858.1
KEGG: sta:STHERM_c05580 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.697
AEJ61968.1
KEGG: sta:STHERM_c16470 lactoylglutathione lyase-like lyase; SPTR: Methylmalonyl-CoA epimerase.
 
   
 0.596
AEJ60676.1
KEGG: sta:STHERM_c04260 hypothetical protein; SPTR: Acetyl xylan esterase.
  
   
 0.581
AEJ60856.1
KEGG: sta:STHERM_c05560 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.570
aroE
3-dehydroquinate dehydratase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
 
   
 0.500
AEJ61710.1
PFAM: Cellulase (glycosyl hydrolase family 5); COGs: COG2730 Endoglucanase; InterPro IPR001547; KEGG: sta:STHERM_c07100 endoglucanase; PFAM: Glycoside hydrolase, family 5; SPTR: Glycoside hydrolase family 5; Belongs to the glycosyl hydrolase 5 (cellulase A) family.
  
     0.497
AEJ60855.1
PFAM: Endonuclease/Exonuclease/phosphatase family; COGs: COG3568 Metal-dependent hydrolase; InterPro IPR005135; KEGG: sta:STHERM_c05550 endonuclease/exonuclease/phosphatase family protein; PFAM: Endonuclease/exonuclease/phosphatase; SPTR: Endonuclease/exonuclease/phosphatase.
       0.476
clpP
ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
       0.473
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.