STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
uxuAMannonate dehydratase; Catalyzes the dehydration of D-mannonate. (360 aa)    
Predicted Functional Partners:
uxaC
PFAM: Glucuronate isomerase; COGs: COG1904 Glucuronate isomerase; HAMAP: Uronate isomerase; InterPro IPR003766; KEGG: sta:STHERM_c04600 uronate isomerase; PFAM: Uronate isomerase; SPTR: Uronate isomerase.
 
  
 0.970
AEJ60700.1
Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198; KEGG: sta:STHERM_c04590 D-mannonate oxidoreductase; PFAM: Short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR.
 
 
 0.927
AEJ60663.1
PFAM: short chain dehydrogenase; TIGRFAM: 2-deoxy-D-gluconate 3-dehydrogenase; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR011286:IPR002198; KEGG: sta:STHERM_c04140 2-deoxy-D-gluconate 3-dehydrogenase; PFAM: Short-chain dehydrogenase/reductase SDR; SPTR: 2-deoxy-D-gluconate 3-dehydrogenase; TIGRFAM: 2-deoxy-D-gluconate 3-dehydrogenase.
  
 
 0.917
AEJ60682.1
PfkB domain protein; PFAM: pfkB family carbohydrate kinase; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: sta:STHERM_c04320 carbohydrate kinase, PfkB family; PFAM: Carbohydrate/purine kinase; SPTR: PfkB domain protein.
 
  
 0.867
AEJ60664.1
6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
     
  0.800
AEJ61985.1
PFAM: Ribulose-phosphate 3 epimerase family; TIGRFAM: ribulose-phosphate 3-epimerase; COGs: COG0036 Pentose-5-phosphate-3-epimerase; InterPro IPR000056; KEGG: sta:STHERM_c16660 ribulose-phosphate 3-epimerase; PFAM: Ribulose-phosphate 3-epimerase; SPTR: Ribulose-phosphate 3-epimerase; TIGRFAM: Ribulose-phosphate 3-epimerase.
     
  0.800
rpiA
Ribose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
     
  0.800
AEJ60683.1
PFAM: KDPG and KHG aldolase; TIGRFAM: Entner-Doudoroff aldolase; COGs: COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase; InterPro IPR000887; KEGG: sta:STHERM_c04330 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase; PFAM: KDPG/KHG aldolase; SPTR: 2-keto-3-deoxy-phosphogluconate aldolase.
 
   
 0.621
AEJ60861.1
Diguanylate cyclase; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160; KEGG: sta:STHERM_c05610 hypothetical protein; PFAM: Diguanylate cyclase, predicted; SMART: Diguanylate cyclase, predicted; SPTR: Diguanylate cyclase; TIGRFAM: Diguanylate cyclase, predicted.
       0.572
AEJ61794.1
PFAM: Glycosyl hydrolase family 67 C-terminus; Glycosyl hydrolase family 67 middle domain; Glycosyl hydrolase family 67 N-terminus; COGs: COG3661 Alpha-glucuronidase; InterPro IPR005154:IPR011100:IPR011099; KEGG: sta:STHERM_c13950 hypothetical protein; PFAM: Glycosyl hydrolase 67 middle; Glycoside hydrolase family 67; Glycosyl hydrolase 67, C-terminal; SPTR: Alpha-glucuronidase.
     0.543
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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