Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
gene fusions
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AEJ60884.1AAA ATPase central domain protein; PFAM: MgsA AAA+ ATPase C terminal; ATPase family associated with various cellular activities (AAA); COGs: COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase; InterPro IPR003593:IPR003959; KEGG: sta:STHERM_c05990 ATPase, AAA family; PFAM: ATPase, AAA-type, core; SMART: ATPase, AAA+ type, core; SPTR: Recombination protein MgsA. (741 aa)    
Predicted Functional Partners:
AEJ60289.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
    
 
 0.770
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
    0.585
AEJ60885.1
KEGG: sta:STHERM_c05980 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.548
AEJ60886.1
Na/Pi-cotransporter II-related protein; PFAM: Na+/Pi-cotransporter; PhoU domain; TIGRFAM: Na/Pi-cotransporter; COGs: COG1283 Na+/phosphate symporter; InterPro IPR004633:IPR003841:IPR008170; KEGG: sta:STHERM_c05970 transporter; PFAM: Na/Pi-cotransporter; PhoU; SPTR: Na/Pi-cotransporter II-related protein; TIGRFAM: Na/Pi co-transporter II-related.
       0.531
AEJ60887.1
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
 
     0.423
AEJ62297.1
Competence/damage-inducible protein CinA; PFAM: Probable molybdopterin binding domain; Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA N-terminal domain; competence/damage-inducible protein CinA C-terminal domain; molybdenum cofactor synthesis domain; COGs: COG1546 Uncharacterized protein (competence- and mitomycin-induced); InterPro IPR001453:IPR008136:IPR008135; KEGG: sta:STHERM_c19900 CinA-like protein; PFAM: CinA, C-terminal; Molybdopterin binding; SPTR: CinA-like protein; TIGRFAM: Competence-induced protein CinA; CinA, C-terminal.
     
 0.423
AEJ61084.1
PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I; COGs: COG1109 Phosphomannomutase; InterPro IPR005844; KEGG: sta:STHERM_c14230 hypothetical protein; PFAM: Alpha-D-phosphohexomutase, alpha/beta/alpha domain I; SPTR: Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I.
  
   0.409
AEJ61503.1
PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, C-terminal domain; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I; COGs: COG1109 Phosphomannomutase; InterPro IPR005844:IPR005845; KEGG: sta:STHERM_c11950 hypothetical protein; PFAM: Alpha-D-phosphohexomutase, alpha/beta/alpha domain I; Alpha-D-phosphohexomutase, alpha/beta/alpha domain II; SPTR: Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I.
  
   0.409
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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