STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ60900.1PFAM: ABC transporter; ABC transporter transmembrane region; COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterPro IPR001140:IPR003439:IPR003593; KEGG: sta:STHERM_c06060 transporter; PFAM: ABC transporter-like; ABC transporter, transmembrane region; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein. (572 aa)    
Predicted Functional Partners:
AEJ60550.1
PFAM: ABC transporter; Oligopeptide/dipeptide transporter, C-terminal region; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; COGs: COG0444 ABC-type dipeptide/oligopeptide/nickel transport system ATPase component; InterPro IPR003439:IPR013563:IPR003593:IPR010066; KEGG: sta:STHERM_c02800 oligopeptide/dipeptide ABC transporter ATPase subunit; PFAM: ABC transporter-like; Oligopeptide/dipeptide ABC transporter, C-terminal; SMART: ATPase, AAA+ type, core; SPTR: Oligopeptide/dipeptide ABC transporter, ATPase subunit; TIGRFAM: Oligopeptide/dipeptide AB [...]
    
0.855
AEJ60899.1
PFAM: ABC transporter; ABC transporter transmembrane region; COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterPro IPR001140:IPR003439:IPR003593; KEGG: sta:STHERM_c06050 transporter; PFAM: ABC transporter-like; ABC transporter, transmembrane region; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein.
 
    
0.822
AEJ60901.1
PFAM: MarR family; COGs: COG1846 Transcriptional regulators; InterPro IPR000835:IPR001367; KEGG: sta:STHERM_c06070 hypothetical protein; PFAM: HTH transcriptional regulator, MarR; SMART: HTH transcriptional regulator, MarR; Iron dependent repressor; SPTR: Transcriptional regulator, MarR family.
  
  
 0.811
AEJ60990.1
PFAM: Pyridine nucleotide-disulphide oxidoreductase; DsrE/DsrF-like family; SirA-like protein; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Rhodanese-like domain; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterProIPR013027:IPR004099:IPR001763:IPR001455:IPR 014865; KEGG: sta:STHERM_c15100 hypothetical protein; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; Rhodanese-like; SirA-like; Protein of unknown function DUF1791; SMART: Rhodanese-like; SPTR: FAD-dependent pyridine nucleoti [...]
  
 
 0.671
AEJ61306.1
PFAM: ABC transporter; COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: sta:STHERM_c10090 transporter; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: Transporter; manually curated.
    
0.608
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
 
 0.602
AEJ61697.1
PFAM: Domain of unknown function DUF140; TIGRFAM: conserved hypothetical integral membrane protein; COGs: COG0767 ABC-type transport system involved in resistance to organic solvents permease component; InterPro IPR003453; KEGG: sta:STHERM_c07230 transporter; PFAM: Protein of unknown function DUF140; SPTR: Putative uncharacterized protein.
  
 
 0.595
AEJ60898.1
KEGG: sta:STHERM_c06040 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.586
infB
Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
  
 
 
 0.581
AEJ60903.1
PFAM: Vacuole effluxer Atg22 like; Major Facilitator Superfamily; InterPro IPR011701; KEGG: sta:STHERM_c06090 transmembrane protein; PFAM: Major facilitator superfamily MFS-1; SPTR: Major facilitator superfamily MFS_1.
     
 0.580
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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