STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ60901.1PFAM: MarR family; COGs: COG1846 Transcriptional regulators; InterPro IPR000835:IPR001367; KEGG: sta:STHERM_c06070 hypothetical protein; PFAM: HTH transcriptional regulator, MarR; SMART: HTH transcriptional regulator, MarR; Iron dependent repressor; SPTR: Transcriptional regulator, MarR family. (147 aa)    
Predicted Functional Partners:
AEJ60899.1
PFAM: ABC transporter; ABC transporter transmembrane region; COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterPro IPR001140:IPR003439:IPR003593; KEGG: sta:STHERM_c06050 transporter; PFAM: ABC transporter-like; ABC transporter, transmembrane region; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein.
  
  
 0.811
AEJ60900.1
PFAM: ABC transporter; ABC transporter transmembrane region; COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterPro IPR001140:IPR003439:IPR003593; KEGG: sta:STHERM_c06060 transporter; PFAM: ABC transporter-like; ABC transporter, transmembrane region; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein.
  
  
 0.811
AEJ60902.1
PFAM: Transcriptional regulator PadR-like family; COGs: COG1695 transcriptional regulator protein; InterPro IPR005149; KEGG: sta:STHERM_c06080 transcriptional regulator, PadR family; PFAM: Transcriptional regulator PadR N-terminal-like; SPTR: Transcriptional regulator, PadR family.
  
  
 0.613
AEJ60903.1
PFAM: Vacuole effluxer Atg22 like; Major Facilitator Superfamily; InterPro IPR011701; KEGG: sta:STHERM_c06090 transmembrane protein; PFAM: Major facilitator superfamily MFS-1; SPTR: Major facilitator superfamily MFS_1.
     
 0.611
AEJ60898.1
KEGG: sta:STHERM_c06040 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.586
AEJ60652.1
Transcriptional regulator with cupin sensor, AraC family; PFAM: AraC-like ligand binding domain; Bacterial regulatory helix-turn-helix proteins, AraC family; COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR018060:IPR013096:IPR000005; KEGG: sta:STHERM_c04010 transcriptional regulator, AraC/XylS family; PFAM: Helix-turn-helix, AraC type; Cupin 2, conserved barrel; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator, AraC family.
 
  
 0.554
AEJ60990.1
PFAM: Pyridine nucleotide-disulphide oxidoreductase; DsrE/DsrF-like family; SirA-like protein; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Rhodanese-like domain; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterProIPR013027:IPR004099:IPR001763:IPR001455:IPR 014865; KEGG: sta:STHERM_c15100 hypothetical protein; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; Rhodanese-like; SirA-like; Protein of unknown function DUF1791; SMART: Rhodanese-like; SPTR: FAD-dependent pyridine nucleoti [...]
  
  
 0.508
AEJ60897.1
Flavodoxin/nitric oxide synthase; PFAM: Flavodoxin; COGs: COG0655 Multimeric flavodoxin WrbA; InterPro IPR008254; KEGG: sta:STHERM_c06030 flavodoxin; PFAM: Flavodoxin/nitric oxide synthase; SPTR: Flavodoxin/nitric oxide synthase.
  
  
 0.477
AEJ60904.1
Cupin 2 conserved barrel domain protein; PFAM: Cupin domain; InterPro IPR013096; KEGG: sta:STHERM_c06100 hypothetical protein; PFAM: Cupin 2, conserved barrel; SPTR: Cupin 2 conserved barrel domain protein.
  
  
 0.409
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
     
 0.408
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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