Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEJ60902.1PFAM: Transcriptional regulator PadR-like family; COGs: COG1695 transcriptional regulator protein; InterPro IPR005149; KEGG: sta:STHERM_c06080 transcriptional regulator, PadR family; PFAM: Transcriptional regulator PadR N-terminal-like; SPTR: Transcriptional regulator, PadR family. (122 aa)    
Predicted Functional Partners:
AEJ60903.1
PFAM: Vacuole effluxer Atg22 like; Major Facilitator Superfamily; InterPro IPR011701; KEGG: sta:STHERM_c06090 transmembrane protein; PFAM: Major facilitator superfamily MFS-1; SPTR: Major facilitator superfamily MFS_1.
     
 0.781
AEJ60901.1
PFAM: MarR family; COGs: COG1846 Transcriptional regulators; InterPro IPR000835:IPR001367; KEGG: sta:STHERM_c06070 hypothetical protein; PFAM: HTH transcriptional regulator, MarR; SMART: HTH transcriptional regulator, MarR; Iron dependent repressor; SPTR: Transcriptional regulator, MarR family.
  
  
 0.606
AEJ60899.1
PFAM: ABC transporter; ABC transporter transmembrane region; COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterPro IPR001140:IPR003439:IPR003593; KEGG: sta:STHERM_c06050 transporter; PFAM: ABC transporter-like; ABC transporter, transmembrane region; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein.
     
 0.558
AEJ60900.1
PFAM: ABC transporter; ABC transporter transmembrane region; COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterPro IPR001140:IPR003439:IPR003593; KEGG: sta:STHERM_c06060 transporter; PFAM: ABC transporter-like; ABC transporter, transmembrane region; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein.
     
 0.558
AEJ60904.1
Cupin 2 conserved barrel domain protein; PFAM: Cupin domain; InterPro IPR013096; KEGG: sta:STHERM_c06100 hypothetical protein; PFAM: Cupin 2, conserved barrel; SPTR: Cupin 2 conserved barrel domain protein.
  
  
 0.505
AEJ60898.1
KEGG: sta:STHERM_c06040 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.426
AEJ60990.1
PFAM: Pyridine nucleotide-disulphide oxidoreductase; DsrE/DsrF-like family; SirA-like protein; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Rhodanese-like domain; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterProIPR013027:IPR004099:IPR001763:IPR001455:IPR 014865; KEGG: sta:STHERM_c15100 hypothetical protein; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; Rhodanese-like; SirA-like; Protein of unknown function DUF1791; SMART: Rhodanese-like; SPTR: FAD-dependent pyridine nucleoti [...]
  
  
 0.420
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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