STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ60904.1Cupin 2 conserved barrel domain protein; PFAM: Cupin domain; InterPro IPR013096; KEGG: sta:STHERM_c06100 hypothetical protein; PFAM: Cupin 2, conserved barrel; SPTR: Cupin 2 conserved barrel domain protein. (100 aa)    
Predicted Functional Partners:
AEJ60905.1
PFAM: Family of unknown function (DUF438); Domain of unknown function (DUF1858); Hemerythrin HHE cation binding domain; COGs: COG2461 conserved hypothetical protein; InterPro IPR015077:IPR007380:IPR012312; KEGG: sta:STHERM_c06110 hypothetical protein; PFAM: Protein of unknown function DUF438; Domain of unknown function DUF1858; Haemerythrin/HHE cation-binding motif; SPTR: Putative uncharacterized protein.
 
     0.677
AEJ62404.1
PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family; AraC-like ligand binding domain; COGs: COG4977 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain; InterPro IPR003313:IPR000005:IPR018060; KEGG: sta:STHERM_c21040 transcriptional regulatory protein; PFAM: AraC protein, arabinose-binding/dimerisation; Helix-turn-helix, AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator, AraC family.
 
 
 0.592
AEJ60903.1
PFAM: Vacuole effluxer Atg22 like; Major Facilitator Superfamily; InterPro IPR011701; KEGG: sta:STHERM_c06090 transmembrane protein; PFAM: Major facilitator superfamily MFS-1; SPTR: Major facilitator superfamily MFS_1.
  
  
 0.492
AEJ60902.1
PFAM: Transcriptional regulator PadR-like family; COGs: COG1695 transcriptional regulator protein; InterPro IPR005149; KEGG: sta:STHERM_c06080 transcriptional regulator, PadR family; PFAM: Transcriptional regulator PadR N-terminal-like; SPTR: Transcriptional regulator, PadR family.
  
    0.488
AEJ61982.1
PFAM: domain; Domain of unknown function; Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895:IPR002880:IPR019752:IPR019456:IPR 001450:IPR011766; KEGG: sta:STHERM_c16630 pyruvate-flavodoxin oxidoreductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin ox [...]
  
 
 0.417
AEJ60901.1
PFAM: MarR family; COGs: COG1846 Transcriptional regulators; InterPro IPR000835:IPR001367; KEGG: sta:STHERM_c06070 hypothetical protein; PFAM: HTH transcriptional regulator, MarR; SMART: HTH transcriptional regulator, MarR; Iron dependent repressor; SPTR: Transcriptional regulator, MarR family.
  
  
 0.409
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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