STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ60908.1PFAM: Metallopeptidase family M24; Creatinase/Prolidase N-terminal domain; COGs: COG0006 Xaa-Pro aminopeptidase; KEGG: sta:STHERM_c06140 M24 family peptidase-like protein; SPTR: Putative uncharacterized protein. (371 aa)    
Predicted Functional Partners:
AEJ60907.1
PFAM: Bacterial extracellular solute-binding protein, family 7; COGs: COG1638 TRAP-type C4-dicarboxylate transport system periplasmic component; InterPro IPR018389; KEGG: sta:STHERM_c06130 transporter; PFAM: Extracellular solute-binding protein, family 7, bacteria; SPTR: Extracellular solute-binding protein, family 7.
 
     0.726
AEJ60910.1
Hypothetical protein; PFAM: Tripartite tricarboxylate transporter TctB family; KEGG: sta:STHERM_c06160 hypothetical protein; SPTR: Putative uncharacterized protein.
 
     0.718
AEJ60909.1
PFAM: Tripartite tricarboxylate transporter family receptor; COGs: COG3181 conserved hypothetical protein; InterPro IPR005064; KEGG: sta:STHERM_c06150 tricarboxylic transport; SPTR: Tricarboxylate-binding protein.
 
     0.706
AEJ60912.1
Oxidoreductase domain protein; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; Oxidoreductase family, C-terminal alpha/beta domain; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104; KEGG: sta:STHERM_c06180 oxidoreductase domain-containing protein; PFAM: Oxidoreductase, N-terminal; Oxidoreductase, C-terminal; SPTR: Oxidoreductase domain protein.
 
   
 0.514
AEJ60676.1
KEGG: sta:STHERM_c04260 hypothetical protein; SPTR: Acetyl xylan esterase.
 
     0.512
AEJ60911.1
Protein of unknown function DUF112 transmembrane; PFAM: Tripartite tricarboxylate transporter TctA family; COGs: COG3333 conserved hypothetical protein; InterPro IPR002823; KEGG: sta:STHERM_c06170 hypothetical protein; PFAM: Protein of unknown function DUF112, transmembrane; SPTR: Putative uncharacterized protein.
 
     0.510
AEJ62280.1
Transketolase domain-containing protein; PFAM: Dehydrogenase E1 component; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; Transketolase, C-terminal domain; Biotin-requiring enzyme; Transketolase, pyrimidine binding domain; TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) synthase III; COGs: COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit; InterProIPR001017:IPR005475:IPR005476:IPR000089:IPR 013751:IPR013747; KEGG: sta:STHERM_c19760 hypothetical protein; PFAM: Tr [...]
  
 
 0.462
AEJ61982.1
PFAM: domain; Domain of unknown function; Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895:IPR002880:IPR019752:IPR019456:IPR 001450:IPR011766; KEGG: sta:STHERM_c16630 pyruvate-flavodoxin oxidoreductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin ox [...]
     
 0.445
AEJ62279.1
PFAM: Peptidase M16C associated; Peptidase M16 inactive domain; COGs: COG1026 Zn-dependent peptidase insulinase-like; InterPro IPR007863:IPR013578; KEGG: sta:STHERM_c19750 presequence protease 1; PFAM: Peptidase M16C associated; Peptidase M16, C-terminal; SPTR: Peptidase M16C associated domain protein.
   
 
 0.433
trpF
PFAM: Indole-3-glycerol phosphate synthase; N-(5'phosphoribosyl)anthranilate (PRA) isomerase; COGs: COG0134 Indole-3-glycerol phosphate synthase; InterPro IPR013798:IPR001240; KEGG: sta:STHERM_c01830 anthranilate synthase component; PFAM: Indole-3-glycerol phosphate synthase; N-(5'phosphoribosyl)anthranilate isomerase (PRAI); SPTR: Indole-3-glycerol phosphate synthase; Belongs to the TrpF family.
  
  
 0.425
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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