Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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AEJ60912.1Oxidoreductase domain protein; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; Oxidoreductase family, C-terminal alpha/beta domain; COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104; KEGG: sta:STHERM_c06180 oxidoreductase domain-containing protein; PFAM: Oxidoreductase, N-terminal; Oxidoreductase, C-terminal; SPTR: Oxidoreductase domain protein. (348 aa)    
Predicted Functional Partners:
AEJ60910.1
Hypothetical protein; PFAM: Tripartite tricarboxylate transporter TctB family; KEGG: sta:STHERM_c06160 hypothetical protein; SPTR: Putative uncharacterized protein.
 
     0.683
AEJ60911.1
Protein of unknown function DUF112 transmembrane; PFAM: Tripartite tricarboxylate transporter TctA family; COGs: COG3333 conserved hypothetical protein; InterPro IPR002823; KEGG: sta:STHERM_c06170 hypothetical protein; PFAM: Protein of unknown function DUF112, transmembrane; SPTR: Putative uncharacterized protein.
       0.615
AEJ61621.1
PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family; COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR000653; KEGG: sta:STHERM_c08130 spore coat polysaccharide biosynthesis protein C; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; SPTR: DegT/DnrJ/EryC1/StrS aminotransferase; Belongs to the DegT/DnrJ/EryC1 family.
 
  
 0.567
AEJ60908.1
PFAM: Metallopeptidase family M24; Creatinase/Prolidase N-terminal domain; COGs: COG0006 Xaa-Pro aminopeptidase; KEGG: sta:STHERM_c06140 M24 family peptidase-like protein; SPTR: Putative uncharacterized protein.
 
   
 0.514
AEJ60676.1
KEGG: sta:STHERM_c04260 hypothetical protein; SPTR: Acetyl xylan esterase.
  
     0.448
AEJ61180.1
PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family; COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR000653; KEGG: sta:STHERM_c08820 aminotransferase, DegT/DnrJ/EryC1/StrS family; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; SPTR: DegT/DnrJ/EryC1/StrS aminotransferase; Belongs to the DegT/DnrJ/EryC1 family.
 
  
 0.427
AEJ60909.1
PFAM: Tripartite tricarboxylate transporter family receptor; COGs: COG3181 conserved hypothetical protein; InterPro IPR005064; KEGG: sta:STHERM_c06150 tricarboxylic transport; SPTR: Tricarboxylate-binding protein.
       0.418
AEJ61620.1
PFAM: Polysaccharide biosynthesis protein; COGs: COG1086 nucleoside-diphosphate sugar epimerase; InterPro IPR003869; KEGG: sta:STHERM_c08150 capsular polysaccharide biosynthesis protein; PFAM: Polysaccharide biosynthesis protein CapD-like; SPTR: Polysaccharide biosynthesis protein CapD.
 
   
 0.402
AEJ60648.1
PFAM: Galactokinase galactose-binding signature; GHMP kinases C terminal; GHMP kinases N terminal domain; TIGRFAM: galactokinase; COGs: COG0153 Galactokinase; InterPro IPR000705:IPR019539:IPR006204:IPR013750; KEGG: sta:STHERM_c03980 galactokinase; PFAM: GHMP kinase; Galactokinase galactose-binding domain; GHMP kinase, C-terminal; SPTR: Galactokinase; TIGRFAM: Galactokinase.
  
 
 0.400
AEJ61164.1
PFAM: Galactokinase galactose-binding signature; GHMP kinases C terminal; GHMP kinases N terminal domain; TIGRFAM: galactokinase; COGs: COG0153 Galactokinase; InterPro IPR019539:IPR006204:IPR013750; KEGG: sta:STHERM_c12660 hypothetical protein; PFAM: GHMP kinase; Galactokinase galactose-binding domain; GHMP kinase, C-terminal; SPTR: Galactokinase.
  
 
 0.400
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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