STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ60913.1GntR domain protein; PFAM: Bacterial regulatory proteins, gntR family; FCD domain; COGs: COG2186 Transcriptional regulators; InterPro IPR000524:IPR011711; KEGG: sta:STHERM_c06190 transcriptional regulatory protein; PFAM: GntR, C-terminal; HTH transcriptional regulator, GntR; SMART: HTH transcriptional regulator, GntR; SPTR: GntR domain protein. (245 aa)    
Predicted Functional Partners:
AEJ61907.1
PFAM: Bacterial regulatory proteins, gntR family; FCD domain; COGs: COG1802 Transcriptional regulators; InterPro IPR000524:IPR011711; KEGG: sta:STHERM_c04230 hypothetical protein; PFAM: HTH transcriptional regulator, GntR; GntR, C-terminal; SMART: HTH transcriptional regulator, GntR; SPTR: Transcriptional regulator, GntR family.
 
  
 0.781
AEJ60673.1
PFAM: Bacterial regulatory proteins, gntR family; FCD domain; COGs: COG1802 Transcriptional regulators; InterPro IPR000524:IPR011711; KEGG: sta:STHERM_c04230 hypothetical protein; PFAM: GntR, C-terminal; HTH transcriptional regulator, GntR; SMART: HTH transcriptional regulator, GntR; SPTR: Transcriptional regulator, GntR family.
 
  
 0.771
AEJ60889.1
PFAM: Bacterial regulatory proteins, gntR family; FCD domain; COGs: COG1802 Transcriptional regulators; InterPro IPR000524:IPR011711; KEGG: sta:STHERM_c05930 transcriptional regulatory protein; PFAM: GntR, C-terminal; HTH transcriptional regulator, GntR; SMART: HTH transcriptional regulator, GntR; SPTR: Transcriptional regulator, GntR family.
 
  
 0.768
AEJ60652.1
Transcriptional regulator with cupin sensor, AraC family; PFAM: AraC-like ligand binding domain; Bacterial regulatory helix-turn-helix proteins, AraC family; COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR018060:IPR013096:IPR000005; KEGG: sta:STHERM_c04010 transcriptional regulator, AraC/XylS family; PFAM: Helix-turn-helix, AraC type; Cupin 2, conserved barrel; SMART: Helix-turn-helix, AraC domain; SPTR: Transcriptional regulator, AraC family.
 
  
 0.535
AEJ60914.1
PFAM: Periplasmic solute binding protein family; COGs: COG0803 ABC-type metal ion transport system periplasmic component/surface adhesin; InterPro IPR006127; KEGG: sta:STHERM_c06200 hypothetical protein; PFAM: ABC transporter metal-binding lipoprotein; SPTR: Periplasmic solute binding protein.
       0.528
AEJ60915.1
PFAM: ABC transporter; COGs: COG1121 ABC-type Mn/Zn transport systems ATPase component; InterPro IPR003439:IPR003593; KEGG: sta:STHERM_c06210 ABC transporter; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein.
       0.528
AEJ61965.1
Transcriptional regulator, LysR family; PFAM: LysR substrate binding domain; Bacterial regulatory helix-turn-helix protein, lysR family; COGs: COG0583 Transcriptional regulator; InterPro IPR000847:IPR005119; KEGG: sta:STHERM_c16440 transcriptional regulatory protein; PFAM: LysR, substrate-binding; HTH transcriptional regulator, LysR; SPTR: Transcriptional regulator, LysR family.
  
  
 0.512
AEJ60917.1
Malic protein NAD-binding protein; PFAM: Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain; COGs: COG0281 Malic enzyme; InterPro IPR012301:IPR012302; KEGG: sta:STHERM_c06230 hypothetical protein; PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; SPTR: Malic protein NAD-binding.
  
    0.493
AEJ60916.1
ABC-type transporter, integral membrane subunit; PFAM: ABC 3 transport family; COGs: COG1108 ABC-type Mn2+/Zn2+ transport systems permease components; InterPro IPR001626; KEGG: sta:STHERM_c06220 ABC transporter; PFAM: ABC-3; SPTR: ABC-3 protein.
  
    0.453
accD
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
  
  
 0.448
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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