STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ60914.1PFAM: Periplasmic solute binding protein family; COGs: COG0803 ABC-type metal ion transport system periplasmic component/surface adhesin; InterPro IPR006127; KEGG: sta:STHERM_c06200 hypothetical protein; PFAM: ABC transporter metal-binding lipoprotein; SPTR: Periplasmic solute binding protein. (318 aa)    
Predicted Functional Partners:
AEJ60915.1
PFAM: ABC transporter; COGs: COG1121 ABC-type Mn/Zn transport systems ATPase component; InterPro IPR003439:IPR003593; KEGG: sta:STHERM_c06210 ABC transporter; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein.
 
 
 0.998
AEJ60916.1
ABC-type transporter, integral membrane subunit; PFAM: ABC 3 transport family; COGs: COG1108 ABC-type Mn2+/Zn2+ transport systems permease components; InterPro IPR001626; KEGG: sta:STHERM_c06220 ABC transporter; PFAM: ABC-3; SPTR: ABC-3 protein.
 
 
 0.997
rpmB
PFAM: Ribosomal L28 family; TIGRFAM: ribosomal protein L28; COGs: COG0227 Ribosomal protein L28; HAMAP: Ribosomal protein L28; InterPro IPR001383; KEGG: sta:STHERM_c02350 50S ribosomal protein L28; PFAM: Ribosomal protein L28; SPTR: 50S ribosomal protein L28; TIGRFAM: Ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.
  
  
 0.655
rpsZ
Ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
  
  
 0.652
AEJ60923.1
PFAM: Iron dependent repressor, metal binding and dimerisation domain; Iron dependent repressor, N-terminal DNA binding domain; COGs: COG1321 Mn-dependent transcriptional regulator protein; InterPro IPR001367; KEGG: sta:STHERM_c06290 iron-dependent repressor; PFAM: Iron dependent repressor; SMART: Iron dependent repressor; SPTR: Iron (Metal) dependent repressor, DtxR family.
  
  
 0.625
AEJ60913.1
GntR domain protein; PFAM: Bacterial regulatory proteins, gntR family; FCD domain; COGs: COG2186 Transcriptional regulators; InterPro IPR000524:IPR011711; KEGG: sta:STHERM_c06190 transcriptional regulatory protein; PFAM: GntR, C-terminal; HTH transcriptional regulator, GntR; SMART: HTH transcriptional regulator, GntR; SPTR: GntR domain protein.
       0.528
AEJ60917.1
Malic protein NAD-binding protein; PFAM: Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain; COGs: COG0281 Malic enzyme; InterPro IPR012301:IPR012302; KEGG: sta:STHERM_c06230 hypothetical protein; PFAM: Malic enzyme, NAD-binding; Malic enzyme, N-terminal; SPTR: Malic protein NAD-binding.
     
 0.487
AEJ62280.1
Transketolase domain-containing protein; PFAM: Dehydrogenase E1 component; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; Transketolase, C-terminal domain; Biotin-requiring enzyme; Transketolase, pyrimidine binding domain; TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) synthase III; COGs: COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit; InterProIPR001017:IPR005475:IPR005476:IPR000089:IPR 013751:IPR013747; KEGG: sta:STHERM_c19760 hypothetical protein; PFAM: Tr [...]
  
  
 0.463
AEJ61554.1
PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: phosphoribosylformylglycinamidine synthase, clade II; COGs: COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase synthetase domain; InterPro IPR000728:IPR010918:IPR010141; KEGG: sta:STHERM_c12510 hypothetical protein; PFAM: AIR synthase related protein, C-terminal; AIR synthase related protein; SPTR: Phosphoribosylformylglycinamidine synthase; TIGRFAM: Phosphoribosylformylglycinamidine synthase, FGAM.
     
 0.429
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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