STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ60923.1PFAM: Iron dependent repressor, metal binding and dimerisation domain; Iron dependent repressor, N-terminal DNA binding domain; COGs: COG1321 Mn-dependent transcriptional regulator protein; InterPro IPR001367; KEGG: sta:STHERM_c06290 iron-dependent repressor; PFAM: Iron dependent repressor; SMART: Iron dependent repressor; SPTR: Iron (Metal) dependent repressor, DtxR family. (156 aa)    
Predicted Functional Partners:
AEJ60922.1
Ferrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
 
  
 0.977
AEJ60921.1
FeoA family protein; PFAM: FeoA domain; COGs: COG1918 Fe2+ transport system protein A; InterPro IPR007167; KEGG: sta:STHERM_c06270 ferrous iron transport protein A; PFAM: Ferrous iron transporter, FeoA subunit; SPTR: FeoA family protein.
 
  
 0.840
AEJ62188.1
PFAM: Ferric uptake regulator family; COGs: COG0735 Fe2+/Zn2+ uptake regulation protein; InterPro IPR002481; KEGG: fnu:FN2045 ferric uptake regulation protein; PFAM: Ferric-uptake regulator; SPTR: Ferric uptake regulator, Fur family; Belongs to the Fur family.
  
  
 0.681
AEJ61698.1
PFAM: ABC transporter; COGs: COG1127 ABC-type transport system involved in resistance to organic solvents ATPase component; InterPro IPR003593:IPR003439; KEGG: sta:STHERM_c07220 transporter; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein.
   
   0.653
AEJ60916.1
ABC-type transporter, integral membrane subunit; PFAM: ABC 3 transport family; COGs: COG1108 ABC-type Mn2+/Zn2+ transport systems permease components; InterPro IPR001626; KEGG: sta:STHERM_c06220 ABC transporter; PFAM: ABC-3; SPTR: ABC-3 protein.
  
  
 0.640
AEJ60914.1
PFAM: Periplasmic solute binding protein family; COGs: COG0803 ABC-type metal ion transport system periplasmic component/surface adhesin; InterPro IPR006127; KEGG: sta:STHERM_c06200 hypothetical protein; PFAM: ABC transporter metal-binding lipoprotein; SPTR: Periplasmic solute binding protein.
  
  
 0.625
AEJ60915.1
PFAM: ABC transporter; COGs: COG1121 ABC-type Mn/Zn transport systems ATPase component; InterPro IPR003439:IPR003593; KEGG: sta:STHERM_c06210 ABC transporter; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein.
  
  
 0.615
AEJ61763.1
Zinc/iron permease; PFAM: ZIP Zinc transporter; COGs: COG0428 divalent heavy-metal cations transporter; InterPro IPR003689; KEGG: sta:STHERM_c13640 hypothetical protein; PFAM: Zinc/iron permease; SPTR: Zinc/iron permease.
  
  
 0.542
AEJ61965.1
Transcriptional regulator, LysR family; PFAM: LysR substrate binding domain; Bacterial regulatory helix-turn-helix protein, lysR family; COGs: COG0583 Transcriptional regulator; InterPro IPR000847:IPR005119; KEGG: sta:STHERM_c16440 transcriptional regulatory protein; PFAM: LysR, substrate-binding; HTH transcriptional regulator, LysR; SPTR: Transcriptional regulator, LysR family.
  
 
 0.502
tpx
Thiol peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily.
  
  
 0.501
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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