STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ60931.1PFAM: Glucokinase; TIGRFAM: glucokinase, proteobacterial type; COGs: COG0837 Glucokinase; InterPro IPR003836; KEGG: sta:STHERM_c06370 glucokinase; PFAM: Glucokinase; SPTR: Glucokinase. (357 aa)    
Predicted Functional Partners:
zwf
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
 
 
 0.930
pgi
PFAM: Phosphoglucose isomerase; COGs: COG0166 Glucose-6-phosphate isomerase; HAMAP: Phosphoglucose isomerase (PGI); InterPro IPR001672; KEGG: sta:STHERM_c20070 glucose-6-phosphate isomerase; PFAM: Phosphoglucose isomerase (PGI); SPTR: Glucose-6-phosphate isomerase; Belongs to the GPI family.
    
 0.926
AEJ61503.1
PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, C-terminal domain; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I; COGs: COG1109 Phosphomannomutase; InterPro IPR005844:IPR005845; KEGG: sta:STHERM_c11950 hypothetical protein; PFAM: Alpha-D-phosphohexomutase, alpha/beta/alpha domain I; Alpha-D-phosphohexomutase, alpha/beta/alpha domain II; SPTR: Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I.
     
 0.912
AEJ60524.1
Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer.
    
 0.905
AEJ60528.1
PFAM: Aldose 1-epimerase; COGs: COG2017 Galactose mutarotase; InterPro IPR008183; KEGG: sta:STHERM_c02600 aldose-epimerase; PFAM: Aldose 1-epimerase; SPTR: Aldose 1-epimerase.
    
 0.905
AEJ62193.1
PFAM: domain; Glycosyl hydrolases family 2, TIM barrel domain; Glycosyl hydrolases family 2, sugar binding domain; COGs: COG3250 Beta-galactosidase/beta-glucuronidase; InterPro IPR006104:IPR006102:IPR006103; KEGG: sta:STHERM_c18890 carbohydrate binding family 6; PFAM: Glycoside hydrolase family 2, carbohydrate-binding; Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich; Glycoside hydrolase family 2, TIM barrel; SPTR: Glycoside hydrolase family 2 sugar binding.
     
 0.902
AEJ60683.1
PFAM: KDPG and KHG aldolase; TIGRFAM: Entner-Doudoroff aldolase; COGs: COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase; InterPro IPR000887; KEGG: sta:STHERM_c04330 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase; PFAM: KDPG/KHG aldolase; SPTR: 2-keto-3-deoxy-phosphogluconate aldolase.
  
 
 0.891
AEJ60409.1
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
    
 0.850
AEJ61645.1
PFAM: Fructose-bisphosphate aldolase class-II; TIGRFAM: ketose-bisphosphate aldolases; fructose-1,6-bisphosphate aldolase, class II, various bacterial and amitochondriate protist; COGs: COG0191 Fructose/tagatose bisphosphate aldolase; InterPro IPR000771:IPR011289; KEGG: sta:STHERM_c07850 fructose-bisphosphate aldolase; PFAM: Ketose-bisphosphate aldolase, class-II; SPTR: Fructose-bisphosphate aldolase; TIGRFAM: Fructose-1,6-bisphosphate aldolase, class II; Ketose-bisphosphate aldolase, class-II.
     
 0.836
xylA
PFAM: Xylose isomerase-like TIM barrel; TIGRFAM: xylose isomerase; COGs: COG2115 Xylose isomerase; HAMAP: Xylose isomerase; InterPro IPR013452:IPR012307:IPR001998; KEGG: sta:STHERM_c16290 xylose isomerase; PFAM: Xylose isomerase, TIM barrel domain; SPTR: Xylose isomerase; TIGRFAM: Xylose isomerase, bacterial type; Belongs to the xylose isomerase family.
     
 0.808
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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