Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEJ60948.1PFAM: Peptidase family M23; COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR016047; KEGG: sta:STHERM_c06540 M23/M37 peptidase domain-containing protein; PFAM: Peptidase M23; SPTR: Peptidase M23. (304 aa)    
Predicted Functional Partners:
AEJ60947.1
PFAM: DHH family; DHHA1 domain; TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; COGs: COG0608 Single-stranded DNA-specific exonuclease; InterPro IPR004610:IPR001667:IPR003156; KEGG: sta:STHERM_c06530 single-stranded-DNA-specific exonuclease; PFAM: Phosphoesterase, RecJ-like; Phosphoesterase, DHHA1; SPTR: Single-stranded-DNA-specific exonuclease RecJ; TIGRFAM: Bacterial RecJ exonuclease.
       0.806
rpsU
PFAM: Ribosomal protein S21; TIGRFAM: ribosomal protein S21; HAMAP: Ribosomal protein S21; InterPro IPR001911; KEGG: sta:STHERM_c06550 30S ribosomal protein S21; PFAM: Ribosomal protein S21; SPTR: 30S ribosomal protein S21; TIGRFAM: Ribosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family.
       0.787
AEJ60946.1
PFAM: Pyrimidine nucleoside phosphorylase C-terminal domain; Glycosyl transferase family, a/b domain; Glycosyl transferase family, helical bundle domain; TIGRFAM: pyrimidine-nucleoside phosphorylase; COGs: COG0213 Thymidine phosphorylase; InterPro IPR018090:IPR017459:IPR000312:IPR013102; KEGG: sta:STHERM_c06520 pyrimidine-nucleoside phosphorylase; PFAM: Glycosyl transferase, family 3; Glycosyl transferase, family 3, N-terminal; Pyrimidine nucleoside phosphorylase, C-terminal; SPTR: Thymidine phosphorylase; TIGRFAM: Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic.
       0.696
AEJ61657.1
Flagellin domain protein; Component of the core of the flagella. Belongs to the bacterial flagellin family.
  
 
 
 0.685
AEJ61705.1
Penicillin-binding protein, 1A family; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase; TIGRFAM: penicillin-binding protein, 1A family; COGs: COG5009 Membrane carboxypeptidase/penicillin-binding protein; InterPro IPR001264:IPR001460:IPR011816; KEGG: sta:STHERM_c07150 penicillin-binding protein; PFAM: Glycosyl transferase, family 51; Penicillin-binding protein, transpeptidase; SPTR: Penicillin-binding protein, 1A family; TIGRFAM: Penicillin-binding protein 1A.
  
   
 0.647
AEJ61308.1
PFAM: Peptidase family M23; LysM domain; COGs: COG4942 Membrane-bound metallopeptidase; InterPro IPR018392:IPR016047:IPR002482; KEGG: sta:STHERM_c10110 LysM domain/M23/M37 peptidase domain-containing protein; PFAM: Peptidase M23; Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding Lysin subgroup; SPTR: Peptidase M23.
 
   
 0.594
AEJ61223.1
Flagellar motor switch protein FliN; FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family.
   
   0.560
AEJ60944.1
PFAM: AzlC protein; TIGRFAM: 4-azaleucine resistance probable transporter AzlC; COGs: COG1296 branched-chain amino acid permease (azaleucine resistance); InterPro IPR011606; KEGG: sta:STHERM_c06500 hypothetical protein; PFAM: AzlC-like; SPTR: AzlC family protein.
       0.414
AEJ60945.1
PFAM: Branched-chain amino acid transport protein (AzlD); InterPro IPR008407; KEGG: sta:STHERM_c06510 hypothetical protein; PFAM: Branched-chain amino acid transport; SPTR: Branched-chain amino acid transport.
       0.414
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
Server load: low (14%) [HD]