STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ60953.1Metallophosphoesterase; PFAM: Calcineurin-like phosphoesterase; COGs: COG2129 phosphoesterase related to the Icc protein; InterPro IPR004843; KEGG: sta:STHERM_c06590 Ser/Thr protein phosphatase family protein; PFAM: Metallophosphoesterase; SPTR: Metallophosphoesterase. (218 aa)    
Predicted Functional Partners:
AEJ60952.1
KEGG: sta:STHERM_c06580 transcriptional regulator; SPTR: Putative uncharacterized protein.
 
     0.942
AEJ60954.1
Tetratricopeptide TPR_2 repeat-containing protein; PFAM: Restriction endonuclease; Tetratricopeptide repeat; InterPro IPR001440:IPR013105:IPR007560:IPR019734; KEGG: sta:STHERM_c06610 TPR domain-containing protein; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; Restriction endonuclease, type IV-like, Mrr; SPTR: Tetratricopeptide TPR_1 repeat-containing protein.
       0.811
AEJ60955.1
Tetratricopeptide TPR_1 repeat-containing protein; PFAM: Tetratricopeptide repeat; InterPro IPR001440:IPR019734; KEGG: sta:STHERM_c06600 TPR domain-containing protein; PFAM: Tetratricopeptide TPR-1; SPTR: Tetratricopeptide TPR_1 repeat-containing protein.
       0.586
AEJ60956.1
Tetratricopeptide TPR_2 repeat-containing protein; PFAM: Tetratricopeptide repeat; InterPro IPR001440:IPR013105:IPR019734; KEGG: sta:STHERM_c06620 TPR domain-containing protein; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; SPTR: Tetratricopeptide TPR_1 repeat-containing protein.
       0.567
greA
Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.
  
     0.493
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.