Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEJ60956.1Tetratricopeptide TPR_2 repeat-containing protein; PFAM: Tetratricopeptide repeat; InterPro IPR001440:IPR013105:IPR019734; KEGG: sta:STHERM_c06620 TPR domain-containing protein; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; SPTR: Tetratricopeptide TPR_1 repeat-containing protein. (649 aa)    
Predicted Functional Partners:
AEJ60955.1
Tetratricopeptide TPR_1 repeat-containing protein; PFAM: Tetratricopeptide repeat; InterPro IPR001440:IPR019734; KEGG: sta:STHERM_c06600 TPR domain-containing protein; PFAM: Tetratricopeptide TPR-1; SPTR: Tetratricopeptide TPR_1 repeat-containing protein.
 
 
 0.946
AEJ62432.1
Tetratricopeptide TPR_1 repeat-containing protein; PFAM: Tetratricopeptide repeat; InterPro IPR001440:IPR013105:IPR019734; KEGG: sta:STHERM_c21310 hypothetical protein; PFAM: Tetratricopeptide TPR-1; Tetratricopeptide TPR2; SPTR: Tetratricopeptide TPR_1 repeat-containing protein.
 
 
 
 0.920
AEJ61711.1
PAS/PAC sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterPro IPR000014:IPR003661:IPR003594; KEGG: sta:STHERM_c07090 sensor protein ZraS; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PA [...]
   
 0.813
AEJ61176.1
PFAM: Tetratricopeptide repeat; COGs: COG5010 Flp pilus assembly protein TadD contains TPR repeats; InterPro IPR001440:IPR011717:IPR013105:IPR019734; KEGG: sta:STHERM_c08780 hypothetical protein; PFAM: Tetratricopeptide TPR-1; Tetratricopeptide TPR-4; Tetratricopeptide TPR2; SMART: Tetratricopeptide repeat; SPTR: Tetratricopeptide TPR_1 repeat-containing protein.
 
 
 
 0.809
AEJ61220.1
OmpA/MotB domain protein; PFAM: OmpA family; COGs: COG1360 Flagellar motor protein; InterPro IPR006665; KEGG: sta:STHERM_c09210 hypothetical protein; PFAM: Outer membrane protein, OmpA/MotB, C-terminal; SPTR: Putative uncharacterized protein.
 
 
 
 0.799
AEJ61441.1
Tetratricopeptide TPR_2 repeat-containing protein; PFAM: Bacterial transcriptional activator domain; Tetratricopeptide repeat; COGs: COG5010 Flp pilus assembly protein TadD contains TPR repeats; InterPro IPR001440:IPR013105:IPR019734; KEGG: sta:STHERM_c11390 hypothetical protein; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; SPTR: Tetratricopeptide TPR_1 repeat-containing protein; tmRNA as predicted by Rfam (RF00023), score 155.20.
 
 
 0.798
AEJ61655.1
PFAM: Tetratricopeptide repeat; COGs: COG5010 Flp pilus assembly protein TadD contains TPR repeats; InterPro IPR019734:IPR001440:IPR013105; KEGG: sta:STHERM_c07750 TPR domain-containing protein; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; SPTR: Tetratricopeptide TPR_1 repeat-containing protein.
 
 
 0.748
AEJ61565.1
Tetratricopeptide TPR_2 repeat-containing protein; PFAM: Tetratricopeptide repeat; InterPro IPR019734:IPR001440:IPR013105; KEGG: sta:STHERM_c08720 TPR domain-containing protein; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; SMART: Tetratricopeptide repeat; SPTR: Tetratricopeptide TPR_1 repeat-containing protein.
 
 
 
 0.743
AEJ61247.1
PFAM: Ankyrin repeat; COGs: COG0666 FOG: Ankyrin repeat; InterPro IPR002110; KEGG: sta:STHERM_c09480 ankyrin repeat-containing protein; PFAM: Ankyrin repeat; SMART: Ankyrin repeat; SPTR: Ankyrin.
 
 0.735
AEJ60954.1
Tetratricopeptide TPR_2 repeat-containing protein; PFAM: Restriction endonuclease; Tetratricopeptide repeat; InterPro IPR001440:IPR013105:IPR007560:IPR019734; KEGG: sta:STHERM_c06610 TPR domain-containing protein; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; Restriction endonuclease, type IV-like, Mrr; SPTR: Tetratricopeptide TPR_1 repeat-containing protein.
 
   
0.720
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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