| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEJ60289.1 | AEJ60960.1 | Spith_0002 | Spith_0681 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | KEGG: sta:STHERM_c06670 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.774 |
| AEJ60289.1 | AEJ61639.1 | Spith_0002 | Spith_1375 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | PFAM: UvrD/REP helicase; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR000212; KEGG: sta:STHERM_c07940 hypothetical protein; PFAM: DNA helicase, UvrD/REP type; SPTR: UvrD/REP helicase. | 0.765 |
| AEJ60289.1 | AEJ61808.1 | Spith_0002 | Spith_1546 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | PFAM: UvrD/REP helicase; TIGRFAM: TIGR00375 family protein; COGs: COG1379 conserved hypothetical protein; InterPro IPR000212; KEGG: sta:STHERM_c14090 hypothetical protein; PFAM: DNA helicase, UvrD/REP type; SPTR: UvrD/REP helicase. | 0.728 |
| AEJ60289.1 | AEJ62422.1 | Spith_0002 | Spith_2167 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | PFAM: UvrD/REP helicase; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR000212; KEGG: sta:STHERM_c21210 DNA helicase; PFAM: DNA helicase, UvrD/REP type; SPTR: UvrD/REP helicase. | 0.765 |
| AEJ60289.1 | mutL | Spith_0002 | Spith_0678 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA mismatch repair protein mutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.906 |
| AEJ60289.1 | mutS | Spith_0002 | Spith_1153 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA mismatch repair protein mutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.889 |
| AEJ60289.1 | polA | Spith_0002 | Spith_0225 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.967 |
| AEJ60958.1 | AEJ60959.1 | Spith_0679 | Spith_0680 | PFAM: FecR protein; KEGG: sta:STHERM_c06640 hypothetical protein; SPTR: Putative uncharacterized protein. | KEGG: sta:STHERM_c06650 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.860 |
| AEJ60958.1 | AEJ60960.1 | Spith_0679 | Spith_0681 | PFAM: FecR protein; KEGG: sta:STHERM_c06640 hypothetical protein; SPTR: Putative uncharacterized protein. | KEGG: sta:STHERM_c06670 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.490 |
| AEJ60958.1 | mutL | Spith_0679 | Spith_0678 | PFAM: FecR protein; KEGG: sta:STHERM_c06640 hypothetical protein; SPTR: Putative uncharacterized protein. | DNA mismatch repair protein mutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.787 |
| AEJ60959.1 | AEJ60958.1 | Spith_0680 | Spith_0679 | KEGG: sta:STHERM_c06650 hypothetical protein; SPTR: Putative uncharacterized protein. | PFAM: FecR protein; KEGG: sta:STHERM_c06640 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.860 |
| AEJ60959.1 | AEJ60960.1 | Spith_0680 | Spith_0681 | KEGG: sta:STHERM_c06650 hypothetical protein; SPTR: Putative uncharacterized protein. | KEGG: sta:STHERM_c06670 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.494 |
| AEJ60959.1 | mutL | Spith_0680 | Spith_0678 | KEGG: sta:STHERM_c06650 hypothetical protein; SPTR: Putative uncharacterized protein. | DNA mismatch repair protein mutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.783 |
| AEJ60960.1 | AEJ60289.1 | Spith_0681 | Spith_0002 | KEGG: sta:STHERM_c06670 hypothetical protein; SPTR: Putative uncharacterized protein. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.774 |
| AEJ60960.1 | AEJ60958.1 | Spith_0681 | Spith_0679 | KEGG: sta:STHERM_c06670 hypothetical protein; SPTR: Putative uncharacterized protein. | PFAM: FecR protein; KEGG: sta:STHERM_c06640 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.490 |
| AEJ60960.1 | AEJ60959.1 | Spith_0681 | Spith_0680 | KEGG: sta:STHERM_c06670 hypothetical protein; SPTR: Putative uncharacterized protein. | KEGG: sta:STHERM_c06650 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.494 |
| AEJ60960.1 | mutL | Spith_0681 | Spith_0678 | KEGG: sta:STHERM_c06670 hypothetical protein; SPTR: Putative uncharacterized protein. | DNA mismatch repair protein mutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.643 |
| AEJ60960.1 | polA | Spith_0681 | Spith_0225 | KEGG: sta:STHERM_c06670 hypothetical protein; SPTR: Putative uncharacterized protein. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.578 |
| AEJ61639.1 | AEJ60289.1 | Spith_1375 | Spith_0002 | PFAM: UvrD/REP helicase; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR000212; KEGG: sta:STHERM_c07940 hypothetical protein; PFAM: DNA helicase, UvrD/REP type; SPTR: UvrD/REP helicase. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.765 |
| AEJ61639.1 | AEJ62422.1 | Spith_1375 | Spith_2167 | PFAM: UvrD/REP helicase; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR000212; KEGG: sta:STHERM_c07940 hypothetical protein; PFAM: DNA helicase, UvrD/REP type; SPTR: UvrD/REP helicase. | PFAM: UvrD/REP helicase; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR000212; KEGG: sta:STHERM_c21210 DNA helicase; PFAM: DNA helicase, UvrD/REP type; SPTR: UvrD/REP helicase. | 0.916 |