STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ60965.1PP-loop domain protein; PFAM: PP-loop family; COGs: COG0037 ATPase of the PP-loop superfamily protein implicated in cell cycle control; InterPro IPR011063; KEGG: sta:STHERM_c06710 PP-loop domain-containing protein; PFAM: PP-loop; SPTR: PP-loop domain protein; Belongs to the TtcA family. (276 aa)    
Predicted Functional Partners:
AEJ60964.1
PFAM: Late competence development protein ComFB; InterPro IPR019657; KEGG: sta:STHERM_c06700 hypothetical protein; PFAM: Late competence development protein ComFB; SPTR: Late competence development protein ComFB.
 
     0.805
AEJ60966.1
Metal dependent phosphohydrolase; PFAM: HD domain; COGs: COG1078 HD superfamily phosphohydrolase; InterPro IPR003607; KEGG: sta:STHERM_c06730 hypothetical protein; SMART: Metal-dependent phosphohydrolase, HD region; SPTR: Metal dependent phosphohydrolase.
       0.802
AEJ60423.1
PFAM: ThiS family; TIGRFAM: thiamine biosynthesis protein ThiS; InterPro IPR003749:IPR010035; KEGG: sta:STHERM_c01480 hypothetical protein; PFAM: ThiamineS; SPTR: Thiamine biosynthesis protein ThiS; TIGRFAM: ThiS, thiamine-biosynthesis.
  
 
 0.700
AEJ61947.1
PFAM: ThiS family; TIGRFAM: thiamine biosynthesis protein ThiS; InterPro IPR010035:IPR003749; KEGG: sta:STHERM_c16270 thiamine biosynthesis protein ThiS; PFAM: ThiamineS; SPTR: Thiamine biosynthesis protein ThiS; TIGRFAM: ThiS, thiamine-biosynthesis.
  
 
 0.589
pth
Peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
  
  
 0.535
AEJ62176.1
Conserved hypothetical protein CHP00268; PFAM: NAD synthase; TIGRFAM: TIGR00268 family protein; COGs: COG1606 ATP-utilizing protein of the PP-loop superfamily; InterPro IPR001962:IPR005232; KEGG: sta:STHERM_c18740 hypothetical protein; PFAM: Asparagine synthase; SPTR: Asparagine synthase; TIGRFAM: Conserved hypothetical protein CHP00268.
 
    0.531
mfd
Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.
  
  
 0.514
metG
Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
 
   
 0.489
rlmE
Ribosomal RNA large subunit methyltransferase E; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
  
  
 0.451
trmB
tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
   
  
 0.430
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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