STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ60977.1Flavodoxin/nitric oxide synthase; PFAM: Flavodoxin; COGs: COG0716 Flavodoxins; InterPro IPR008254; KEGG: tle:Tlet_1577 flavodoxin; PFAM: Flavodoxin/nitric oxide synthase; SPTR: Flavodoxin/nitric oxide synthase. (162 aa)    
Predicted Functional Partners:
AEJ61982.1
PFAM: domain; Domain of unknown function; Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895:IPR002880:IPR019752:IPR019456:IPR 001450:IPR011766; KEGG: sta:STHERM_c16630 pyruvate-flavodoxin oxidoreductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin ox [...]
     
 0.556
AEJ60978.1
Hypothetical protein.
       0.507
AEJ60979.1
Abortive infection protein; PFAM: CAAX amino terminal protease family; InterPro IPR003675; KEGG: rrs:RoseRS_3666 abortive infection protein; PFAM: Abortive infection protein; SPTR: Abortive infection protein.
       0.507
AEJ60720.1
PFAM: Acetyl xylan esterase (AXE1); COGs: COG3458 Acetyl esterase (deacetylase); InterPro IPR008391; KEGG: sta:STHERM_c04720 acetyl xylan esterase; PFAM: Acetyl xylan esterase; SPTR: Cephalosporin-C deacetylase.
  
     0.469
cas1-2
CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
   
   0.453
AEJ62532.1
PFAM: NAD dependent epimerase/dehydratase family; COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: sta:STHERM_c22320 hypothetical protein; PFAM: NAD-dependent epimerase/dehydratase; SPTR: NAD-dependent epimerase/dehydratase.
  
     0.443
AEJ60307.1
PFAM: Alpha amylase, catalytic domain; COGs: COG0366 Glycosidase; InterPro IPR006047:IPR006589; KEGG: sta:STHERM_c00200 hypothetical protein; PFAM: Glycosyl hydrolase, family 13, catalytic region; SMART: Glycosyl hydrolase, family 13, subfamily, catalytic region; SPTR: Alpha amylase catalytic region.
  
     0.437
AEJ62099.1
Hypothetical protein; PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); KEGG: sta:STHERM_c17700 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.419
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.