STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ60983.1PAS modulated sigma54 specific transcriptional regulator, Fis family; PFAM: Bacterial regulatory protein, Fis family; Sigma-54 interaction domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG3829 Transcriptional regulator containing PAS AAA-type ATPase and DNA-binding domains; InterProIPR000014:IPR013656:IPR002078:IPR002197:IPR 003593; KEGG: sta:STHERM_c15170 transcriptional regulatory protein; PFAM: RNA polymerase sigma factor 54, interaction; PAS fold-4; Helix-turn-helix, Fis-type; SMART: ATPase, AAA+ type, core; PAS; SPTR: PAS modulated sigma54 specific transcriptional regulator, [...] (457 aa)    
Predicted Functional Partners:
AEJ60329.1
PFAM: Sigma-54 interaction domain; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR002078:IPR003593; KEGG: sta:STHERM_c00420 transcriptional regulatory protein; PFAM: RNA polymerase sigma factor 54, interaction; SMART: ATPase, AAA+ type, core; SPTR: Sigma 54 interacting domain protein.
  
  
 
0.915
AEJ62495.1
RNA polymerase, sigma 54 subunit, RpoN; PFAM: Sigma-54 factor, Activator interacting domain (AID); Sigma-54 factor, core binding domain; Sigma-54, DNA binding domain; TIGRFAM: RNA polymerase sigma-54 factor; COGs: COG1508 DNA-directed RNA polymerase specialized sigma subunit sigma54 homolog; InterPro IPR000394:IPR007046:IPR007634; KEGG: sta:STHERM_c21940 RNA polymerase sigma-54 factor; PFAM: RNA polymerase sigma factor 54, DNA-binding; RNA polymerase sigma factor 54; RNA polymerase sigma factor 54, core-binding; SPTR: RNA polymerase, sigma 54 subunit, RpoN; TIGRFAM: RNA polymerase sigm [...]
 
   
 0.804
AEJ60982.1
PFAM: Protein of unknown function DUF134; COGs: COG1342 DNA-binding protein; HAMAP: UPF0251 protein; InterPro IPR002852; KEGG: sta:STHERM_c15180 DNA-binding protein; PFAM: Uncharacterised protein family UPF0251; SPTR: UPF0251 protein SpithDRAFT_1522; Belongs to the UPF0251 family.
       0.647
AEJ60984.1
PFAM: Dinitrogenase iron-molybdenum cofactor; InterPro IPR003731; KEGG: sta:STHERM_c15160 hypothetical protein; PFAM: Dinitrogenase iron-molybdenum cofactor biosynthesis; SPTR: Dinitrogenase iron-molybdenum cofactor biosynthesis protein.
       0.472
AEJ60985.1
KEGG: sta:STHERM_c15150 hypothetical protein; SPTR: Putative uncharacterized protein; manually curated.
 
     0.468
AEJ60981.1
AAA ATPase; InterPro IPR003593; KEGG: sta:STHERM_c15210 hypothetical protein; SMART: ATPase, AAA+ type, core; SPTR: AAA ATPase.
       0.434
AEJ60715.1
Response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PFAM: EAL domain; Response regulator receiver domain; GGDEF domain; PAS fold; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain; COGs: COG2200 FOG: EAL domain; InterProIPR000014:IPR000160:IPR001789:IPR001633:IPR 013767; KEGG: sta:STHERM_c04670 hypothetical protein; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; Signal transduction response regulator, receiver region; PAS fold; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclas [...]
     
 0.403
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.