STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
AEJ60989.1Protein of unknown function DUF6 transmembrane; PFAM: EamA-like transporter family; InterPro IPR000620; KEGG: sta:STHERM_c15110 transporter; PFAM: Protein of unknown function DUF6, transmembrane; SPTR: Putative uncharacterized protein. (302 aa)    
Predicted Functional Partners:
AEJ60988.1
KEGG: sta:STHERM_c15120 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.538
secY
Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
   
 
 0.501
AEJ62037.1
Pentapeptide repeat protein; COGs: COG1357 Uncharacterized low-complexity protein; InterPro IPR001646; KEGG: sta:STHERM_c17050 pentapeptide protein; PFAM: Pentapeptide repeat; SPTR: Pentapeptide repeat protein.
   
 
 0.478
AEJ60944.1
PFAM: AzlC protein; TIGRFAM: 4-azaleucine resistance probable transporter AzlC; COGs: COG1296 branched-chain amino acid permease (azaleucine resistance); InterPro IPR011606; KEGG: sta:STHERM_c06500 hypothetical protein; PFAM: AzlC-like; SPTR: AzlC family protein.
 
     0.407
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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