STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ61010.1PFAM: DsrE/DsrF-like family; TIGRFAM: sulfur relay protein TusD/DsrE; COGs: COG1553 conserved hypothetical protein involved in intracellular sulfur reduction; InterPro IPR003787; KEGG: tna:CTN_1597 DsrE family protein; PFAM: Sulphur relay, DsrE-like protein; SPTR: DsrE family protein. (118 aa)    
Predicted Functional Partners:
AEJ61009.1
COGs: COG2923 Uncharacterized protein involved in the oxidation of intracellular sulfur; KEGG: trq:TRQ2_1815 uncharacterized protein involved in the oxidation of intracellular sulfur-like protein; SPTR: Uncharacterized protein involved in the oxidation of intracellular sulfur-like protein.
  
 
 0.978
AEJ61012.1
PFAM: SirA-like protein; InterPro IPR001455; KEGG: tnp:Tnap_1770 SirA family protein; PFAM: SirA-like; SPTR: SirA-like domain-containing protein; Belongs to the sulfur carrier protein TusA family.
 
  
 0.974
AEJ61008.1
PFAM: DsrH like protein; TIGRFAM: sulfur relay protein TusB/DsrH; COGs: COG2168 conserved hypothetical protein; InterPro IPR007215; KEGG: tnp:Tnap_1774 DsrH family protein; PFAM: Sulphur relay, TusB/DsrH; SPTR: Sulfur relay protein TusB/DsrH; TIGRFAM: Sulphur relay, TusB/DsrH.
  
 
 0.960
AEJ61011.1
PFAM: YeeE/YedE family (DUF395); InterPro IPR007272; KEGG: tle:Tlet_1313 protein of unknown function DUF395 YeeE/YedE; PFAM: Protein of unknown function DUF395, YeeE/YedE; SPTR: Putative uncharacterized protein.
 
    0.951
AEJ60990.1
PFAM: Pyridine nucleotide-disulphide oxidoreductase; DsrE/DsrF-like family; SirA-like protein; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Rhodanese-like domain; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterProIPR013027:IPR004099:IPR001763:IPR001455:IPR 014865; KEGG: sta:STHERM_c15100 hypothetical protein; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; Rhodanese-like; SirA-like; Protein of unknown function DUF1791; SMART: Rhodanese-like; SPTR: FAD-dependent pyridine nucleoti [...]
  
  
 0.762
gcvH-2
Glycine cleavage H-protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
       0.723
AEJ61445.1
Hypothetical protein; COGs: COG1148 Heterodisulfide reductase subunit A and related polyferredoxins; KEGG: tma:TM1174 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.697
AEJ61941.1
PFAM: SirA-like protein; Nitrite and sulphite reductase 4Fe-4S domain; Nitrite/Sulfite reductase ferredoxin-like half domain; COGs: COG0155 Sulfite reductase beta subunit (hemoprotein); InterPro IPR005117:IPR006067:IPR001455; KEGG: sta:STHERM_c16210 ferredoxin-nitrite reductase; PFAM: Nitrite/sulphite reductase 4Fe-4S region; Nitrite/sulphite reductase, hemoprotein beta-component, ferrodoxin-like; SirA-like; SPTR: Ferredoxin--nitrite reductase.
  
  
 0.659
AEJ61943.1
PFAM: SirA-like protein; InterPro IPR001455; KEGG: sta:STHERM_c16230 hypothetical protein; PFAM: SirA-like; SPTR: SirA-like domain-containing protein; Belongs to the sulfur carrier protein TusA family.
  
  
 0.618
AEJ61013.1
Dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase; COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterPro IPR006258:IPR013027:IPR004099; KEGG: sta:STHERM_c14890 dihydrolipoyl dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; SPTR: Dihydrolipoyl dehydrogenase; TIGRFAM: Dihydrolipoamide dehydrogenase.
       0.529
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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