Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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AEJ61012.1PFAM: SirA-like protein; InterPro IPR001455; KEGG: tnp:Tnap_1770 SirA family protein; PFAM: SirA-like; SPTR: SirA-like domain-containing protein; Belongs to the sulfur carrier protein TusA family. (80 aa)    
Predicted Functional Partners:
AEJ61010.1
PFAM: DsrE/DsrF-like family; TIGRFAM: sulfur relay protein TusD/DsrE; COGs: COG1553 conserved hypothetical protein involved in intracellular sulfur reduction; InterPro IPR003787; KEGG: tna:CTN_1597 DsrE family protein; PFAM: Sulphur relay, DsrE-like protein; SPTR: DsrE family protein.
 
  
 0.972
AEJ61011.1
PFAM: YeeE/YedE family (DUF395); InterPro IPR007272; KEGG: tle:Tlet_1313 protein of unknown function DUF395 YeeE/YedE; PFAM: Protein of unknown function DUF395, YeeE/YedE; SPTR: Putative uncharacterized protein.
 
  
 0.959
AEJ61009.1
COGs: COG2923 Uncharacterized protein involved in the oxidation of intracellular sulfur; KEGG: trq:TRQ2_1815 uncharacterized protein involved in the oxidation of intracellular sulfur-like protein; SPTR: Uncharacterized protein involved in the oxidation of intracellular sulfur-like protein.
     
 0.751
AEJ61008.1
PFAM: DsrH like protein; TIGRFAM: sulfur relay protein TusB/DsrH; COGs: COG2168 conserved hypothetical protein; InterPro IPR007215; KEGG: tnp:Tnap_1774 DsrH family protein; PFAM: Sulphur relay, TusB/DsrH; SPTR: Sulfur relay protein TusB/DsrH; TIGRFAM: Sulphur relay, TusB/DsrH.
     
 0.723
AEJ61445.1
Hypothetical protein; COGs: COG1148 Heterodisulfide reductase subunit A and related polyferredoxins; KEGG: tma:TM1174 hypothetical protein; SPTR: Putative uncharacterized protein.
 
   
 0.706
AEJ61899.1
PFAM: Aminotransferase class-V; COGs: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase; InterPro IPR000192; KEGG: sta:STHERM_c15870 cysteine desulfurase; PFAM: Aminotransferase, class V/Cysteine desulfurase; SPTR: Cysteine desulfurase.
   
 
 0.706
gcvH-2
Glycine cleavage H-protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
       0.696
AEJ60990.1
PFAM: Pyridine nucleotide-disulphide oxidoreductase; DsrE/DsrF-like family; SirA-like protein; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Rhodanese-like domain; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterProIPR013027:IPR004099:IPR001763:IPR001455:IPR 014865; KEGG: sta:STHERM_c15100 hypothetical protein; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; Rhodanese-like; SirA-like; Protein of unknown function DUF1791; SMART: Rhodanese-like; SPTR: FAD-dependent pyridine nucleoti [...]
  
  
 0.688
AEJ61013.1
Dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase; COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterPro IPR006258:IPR013027:IPR004099; KEGG: sta:STHERM_c14890 dihydrolipoyl dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; SPTR: Dihydrolipoyl dehydrogenase; TIGRFAM: Dihydrolipoamide dehydrogenase.
       0.509
AEJ60646.1
Glycoside hydrolase clan GH-D; PFAM: Melibiase; COGs: COG3345 Alpha-galactosidase; InterPro IPR000111; KEGG: sta:STHERM_c03960 alpha-galactosidase; PFAM: Glycoside hydrolase, clan GH-D; SPTR: Glycoside hydrolase clan GH-D.
  
     0.463
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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