STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEJ61016.1PFAM: Response regulator receiver domain; InterPro IPR001789; KEGG: sta:STHERM_c14860 hypothetical protein; PFAM: Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region; SPTR: Response regulator receiver. (126 aa)    
Predicted Functional Partners:
AEJ62092.1
PFAM: Histidine kinase; Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG3920 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR011495:IPR003594:IPR 000014; KEGG: sta:STHERM_c17620 sensor histidine kinase; PFAM: ATP-binding region, ATPase-like; PAS fold; Signal transduction response regulator, receiver region; Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor region; SMART: Signal transduction response regulator, receiver region; PAS; ATP-binding [...]
 
 
 
 0.809
AEJ62242.1
PFAM: Histidine kinase; 5TMR of 5TMR-LYT; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG3920 Signal transduction histidine kinase; InterProIPR011620:IPR013767:IPR011495:IPR003594:IPR 000014:IPR001610; KEGG: sta:STHERM_c19380 hypothetical protein; PFAM: Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor region; PAS fold; Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region; ATP-binding region, ATPase-like; SMART: PAS; PAC motif; ATP-binding region, ATPase-like; SPTR: Signal [...]
 
 
 
 0.795
AEJ62248.1
PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; TIGRFAM: PAS domain S-box; COGs: COG3920 Signal transduction histidine kinase; InterPro IPR011495:IPR003594:IPR000014; KEGG: sta:STHERM_c19440 sensory box histidine kinase; PFAM: Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor region; ATP-binding region, ATPase-like; SPTR: Signal transduction histidine kinase; TIGRFAM: PAS.
 
 
 
 0.792
AEJ60538.1
PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; COGs: COG3920 Signal transduction histidine kinase; InterPro IPR011495:IPR003594; KEGG: sta:STHERM_c02710 sensor protein; PFAM: Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor region; ATP-binding region, ATPase-like; SPTR: Signal transduction histidine kinase.
 
 
 
 0.791
AEJ62414.1
Putative signal transduction histidine kinase; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; COGs: COG3920 Signal transduction histidine kinase; InterPro IPR003594; KEGG: sta:STHERM_c21140 signal transduction histidine kinase; PFAM: ATP-binding region, ATPase-like; SMART: ATP-binding region, ATPase-like; SPTR: Putative signal transduction histidine kinase.
 
   
 0.780
AEJ61423.1
PFAM: Histidine kinase; COGs: COG3920 Signal transduction histidine kinase; InterPro IPR003660:IPR011495; KEGG: sta:STHERM_c11210 hypothetical protein; PFAM: Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor region; HAMP linker domain; SPTR: Signal transduction histidine kinase.
  
   
 0.768
AEJ61223.1
Flagellar motor switch protein FliN; FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family.
  
  
 0.726
AEJ61015.1
PFAM: Glycosyl transferase family 2; COGs: COG0463 Glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: sta:STHERM_c14870 minor teichoic acid biosynthesis protein GgaA; PFAM: Glycosyl transferase, family 2; SPTR: Glycosyl transferase family 2.
  
  
 0.632
AEJ60614.1
Multi-sensor signal transduction histidine kinase; PFAM: Ammonium Transporter Family; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Hpt domain; TIGRFAM: ammonium transporter; COGs: COG0004 Ammonia permease; InterPro IPR001905:IPR003594:IPR013767:IPR008207; KEGG: sta:STHERM_c03600 ammonia permease with sensory box/GGDEF domains; PFAM: Ammonium transporter; PAS fold; Signal transduction histidine kinase, phosphotransfer (Hpt) region; ATP-binding region, ATPase-like; SMART: ATP-binding region, ATPase-like; SPTR: Multi-sensor signal transduction histidine kinase; TIGRFAM: Ammoni [...]
  
 
 0.579
AEJ60715.1
Response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PFAM: EAL domain; Response regulator receiver domain; GGDEF domain; PAS fold; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain; COGs: COG2200 FOG: EAL domain; InterProIPR000014:IPR000160:IPR001789:IPR001633:IPR 013767; KEGG: sta:STHERM_c04670 hypothetical protein; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; Signal transduction response regulator, receiver region; PAS fold; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclas [...]
  
 
 0.508
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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