STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ61050.1PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region; COGs: COG0295 Cytidine deaminase; InterPro IPR002125; KEGG: sta:STHERM_c14570 hypothetical protein; PFAM: CMP/dCMP deaminase, zinc-binding; SPTR: CMP/dCMP deaminase zinc-binding. (127 aa)    
Predicted Functional Partners:
AEJ61504.1
TGS domain-containing protein; PFAM: Phosphoribulokinase / Uridine kinase family; COGs: COG0572 Uridine kinase; InterPro IPR003593:IPR004095; KEGG: sta:STHERM_c11970 hypothetical protein; PFAM: TGS; SMART: ATPase, AAA+ type, core; SPTR: TGS domain-containing protein.
    
 0.924
AEJ61184.1
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
  
  
  0.921
AEJ62523.1
PFAM: Phosphorylase superfamily; TIGRFAM: purine-nucleoside phosphorylase, family 1 (deoD); COGs: COG0813 Purine-nucleoside phosphorylase; HAMAP: Purine nucleoside phosphorylase deoD-type; InterPro IPR004402:IPR000845; KEGG: sta:STHERM_c22230 purine nucleoside phosphorylase DeoD-type; PFAM: Nucleoside phosphorylase; SPTR: Purine-nucleoside phosphorylase; TIGRFAM: Purine nucleoside phosphorylase.
  
 
 0.919
surE
Multifunctional protein surE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
 0.903
AEJ61048.1
PFAM: Protein of unknown function (DUF1576); InterPro IPR011470; KEGG: sbu:SpiBuddy_2939 hypothetical protein; PFAM: Protein of unknown function DUF1576; SPTR: Putative uncharacterized protein.
       0.773
AEJ61049.1
KEGG: sbu:SpiBuddy_2940 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.773
era
GTP-binding protein Era-like-protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
  
  
 0.684
glyQS
glycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family.
  
    0.610
AEJ61047.1
KEGG: sta:STHERM_c14590 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.445
AEJ61271.1
PFAM: PhoH-like protein; COGs: COG1702 Phosphate starvation-inducible protein PhoH predicted ATPase; InterPro IPR003714; KEGG: sta:STHERM_c09740 PhoH-like protein; PFAM: PhoH-like protein; SPTR: PhoH family protein.
  
    0.415
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.