STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ61052.1PFAM: Cation transport protein; TIGRFAM: potassium uptake protein, TrkH family; COGs: COG0168 Trk-type K+ transport systems membrane components; InterPro IPR003445; KEGG: sta:STHERM_c14550 hypothetical protein; PFAM: Cation transporter; SPTR: Cation transporter. (481 aa)    
Predicted Functional Partners:
AEJ61053.1
PFAM: TrkA-N domain; TrkA-C domain; COGs: COG0569 K+ transport systems NAD-binding component; InterPro IPR003148:IPR006037; KEGG: sta:STHERM_c14540 trk system potassium uptake protein TrkA; PFAM: Regulator of K+ conductance, N-terminal; Regulator of K+ conductance, C-terminal; SPTR: TrkA-N domain protein.
 
 
 0.992
AEJ61982.1
PFAM: domain; Domain of unknown function; Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895:IPR002880:IPR019752:IPR019456:IPR 001450:IPR011766; KEGG: sta:STHERM_c16630 pyruvate-flavodoxin oxidoreductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin ox [...]
   
 
 0.698
ilvD
PFAM: Dehydratase family; TIGRFAM: dihydroxy-acid dehydratase; COGs: COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; HAMAP: Dihydroxy-acid dehydratase; InterPro IPR004404:IPR000581; KEGG: sta:STHERM_c14560 dihydroxy-acid dehydratase; PFAM: Dihydroxy-acid/6-phosphogluconate dehydratase; SPTR: Dihydroxy-acid dehydratase; TIGRFAM: Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
  
    0.600
AEJ61054.1
PFAM: Domain of unknown function (DUF303); InterPro IPR005181; KEGG: sta:STHERM_c14530 sialate O-acetylesterase precursor; PFAM: Protein of unknown function DUF303, acetylesterase putative; SPTR: Sialate O-acetylesterase.
       0.536
AEJ61055.1
PFAM: Cellulase (glycosyl hydrolase family 5); InterPro IPR001547; KEGG: sta:STHERM_c14520 endo-1-4-beta glucanase, glycosyl hydrolase family 5; PFAM: Glycoside hydrolase, family 5; SPTR: Cellulase; Belongs to the glycosyl hydrolase 5 (cellulase A) family.
       0.411
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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