STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ61056.1PFAM: Bacterial regulatory protein, arsR family; InterPro IPR001845; KEGG: sta:STHERM_c14510 transcriptional regulatory protein; PFAM: HTH transcriptional regulator, ArsR; SMART: HTH transcriptional regulator, ArsR; SPTR: Transcriptional regulator, ArsR family. (100 aa)    
Predicted Functional Partners:
AEJ61057.1
PFAM: E1-E2 ATPase; haloacid dehalogenase-like hydrolase; TIGRFAM: heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase; COGs: COG2217 Cation transport ATPase; InterProIPR006404:IPR006416:IPR001757:IPR008250:IPR 005834; KEGG: sta:STHERM_c14500 zinc-transporting ATPase; PFAM: ATPase, P-type, ATPase-associated region; Haloacid dehalogenase-like hydrolase; SPTR: Heavy metal translocating P-type ATPase; TIGRFAM: ATPase, P-type, heavy metal translocating; ATPase, P-type, heavy metal-(C [...]
 
  
 0.921
AEJ61000.1
PFAM: E1-E2 ATPase; Heavy-metal-associated domain; haloacid dehalogenase-like hydrolase; TIGRFAM: copper ion binding protein; heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; COGs: COG2217 Cation transport ATPase; InterProIPR006403:IPR006416:IPR001757:IPR006121:IPR 008250:IPR005834; KEGG: sta:STHERM_c15000 transporter; PFAM: ATPase, P-type, ATPase-associated region; Heavy metal transport/detoxification protein; Haloacid dehalogenase-like hydrolase; SPTR: Heavy metal translocating P-type ATPase; TIGRFAM: ATPase, P-type, heavy metal t [...]
 
  
 0.589
AEJ61055.1
PFAM: Cellulase (glycosyl hydrolase family 5); InterPro IPR001547; KEGG: sta:STHERM_c14520 endo-1-4-beta glucanase, glycosyl hydrolase family 5; PFAM: Glycoside hydrolase, family 5; SPTR: Cellulase; Belongs to the glycosyl hydrolase 5 (cellulase A) family.
       0.519
AEJ61982.1
PFAM: domain; Domain of unknown function; Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895:IPR002880:IPR019752:IPR019456:IPR 001450:IPR011766; KEGG: sta:STHERM_c16630 pyruvate-flavodoxin oxidoreductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin ox [...]
     
 0.473
AEJ60990.1
PFAM: Pyridine nucleotide-disulphide oxidoreductase; DsrE/DsrF-like family; SirA-like protein; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Rhodanese-like domain; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterProIPR013027:IPR004099:IPR001763:IPR001455:IPR 014865; KEGG: sta:STHERM_c15100 hypothetical protein; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; Rhodanese-like; SirA-like; Protein of unknown function DUF1791; SMART: Rhodanese-like; SPTR: FAD-dependent pyridine nucleoti [...]
  
  
 0.432
AEJ61449.1
PFAM: Bacterial regulatory protein, arsR family; InterPro IPR001845; KEGG: sta:STHERM_c11420 transcriptional regulator; PFAM: HTH transcriptional regulator, ArsR; SMART: HTH transcriptional regulator, ArsR; SPTR: Transcriptional regulator, ArsR family.
  
     0.420
AEJ61054.1
PFAM: Domain of unknown function (DUF303); InterPro IPR005181; KEGG: sta:STHERM_c14530 sialate O-acetylesterase precursor; PFAM: Protein of unknown function DUF303, acetylesterase putative; SPTR: Sialate O-acetylesterase.
       0.409
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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