STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ61059.1PFAM: ABC transporter; COGs: COG1122 ABC-type cobalt transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: sta:STHERM_c14480 membrane associated ATPase; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter related protein. (237 aa)    
Predicted Functional Partners:
AEJ61058.1
ABC-type transporter, integral membrane subunit; PFAM: Cobalt transport protein; InterPro IPR003339; KEGG: sta:STHERM_c14490 hypothetical protein; PFAM: Cobalt transport protein; SPTR: Cobalt transport protein.
 
 0.998
AEJ61060.1
PFAM: BioY family; COGs: COG1268 conserved hypothetical protein; InterPro IPR003784; KEGG: sta:STHERM_c14470 biotin synthesis protein BioY; PFAM: BioY protein; SPTR: BioY protein.
 
 
 0.993
AEJ61743.1
Cobalamin (vitamin B12) biosynthesis CbiM protein; PFAM: Cobalt uptake substrate-specific transmembrane region; COGs: COG0310 ABC-type Co2+ transport system permease component; InterPro IPR002751; KEGG: sta:STHERM_c13440 hypothetical protein; PFAM: Cobalamin (vitamin B12) biosynthesis CbiM; SPTR: Cobalamin (Vitamin B12) biosynthesis CbiM protein.
 
 
 0.821
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
 
    0.728
AEJ60549.1
PFAM: ABC transporter; Oligopeptide/dipeptide transporter, C-terminal region; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; COGs: COG0444 ABC-type dipeptide/oligopeptide/nickel transport system ATPase component; InterPro IPR003439:IPR013563:IPR003593:IPR010066; KEGG: sta:STHERM_c02790 oligopeptide/dipeptide ABC transporter ATP-binding protein-like protein; PFAM: ABC transporter-like; Oligopeptide/dipeptide ABC transporter, C-terminal; SMART: ATPase, AAA+ type, core; SPTR: Oligopeptide/dipeptide ABC transporter, ATPase subunit; TIGRFAM: Oligope [...]
 
    
0.633
truA
tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
  
  
 0.621
rplN
Ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
 
  
 0.534
rpsK
30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.
 
  
 0.534
rpsE
Ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.
 
    0.524
AEJ60487.1
PFAM: Protein of unknown function DUF137; COGs: COG1701 conserved hypothetical protein; InterPro IPR002855; KEGG: sta:STHERM_c02160 hypothetical protein; PFAM: Protein of unknown function DUF137; SPTR: Pantothenate synthetase.
  
     0.471
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.