STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ61081.1HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; COGs: COG0637 phosphatase/phosphohexomutase; InterPro IPR006402:IPR005834; KEGG: sta:STHERM_c14260 GS1-like protein; PFAM: Haloacid dehalogenase-like hydrolase; SPTR: HAD-superfamily hydrolase, subfamily IA, variant 3; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3. (237 aa)    
Predicted Functional Partners:
trpS
tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.
       0.786
AEJ61082.1
HhH-GPD family protein; PFAM: Sugar-specific transcriptional regulator TrmB; HhH-GPD superfamily base excision DNA repair protein; COGs: COG1194 A/G-specific DNA glycosylase; InterPro IPR003265; KEGG: sta:STHERM_c14250 A/G-specific adenine glycosylase; PFAM: HhH-GPD domain; SMART: HhH-GPD domain; SPTR: HhH-GPD family protein.
       0.778
AEJ61827.1
PFAM: Glycosyl hydrolase family 65, C-terminal domain; Glycosyl hydrolase family 65 central catalytic domain; Glycosyl hydrolase family 65, N-terminal domain; COGs: COG1554 Trehalose and maltose hydrolase (possible phosphorylase); InterPro IPR005196:IPR005195:IPR005194; KEGG: sta:STHERM_c15330 kojibiose phosphorylase; PFAM: Glycoside hydrolase family 65, central catalytic; Glycoside hydrolase family 65, N-terminal; Glycoside hydrolase, family 65, C-terminal; SPTR: Glycoside hydrolase family 65 central catalytic.
 
  
 0.710
AEJ61826.1
PFAM: Glycosyl hydrolase family 65 central catalytic domain; Glycosyl hydrolase family 65, N-terminal domain; COGs: COG1554 Trehalose and maltose hydrolase (possible phosphorylase); InterPro IPR005196:IPR005195; KEGG: sta:STHERM_c15320 kojibiose phosphorylase; PFAM: Glycoside hydrolase family 65, central catalytic; Glycoside hydrolase family 65, N-terminal; SPTR: Glycoside hydrolase family 65 central catalytic.
 
  
 0.672
AEJ62280.1
Transketolase domain-containing protein; PFAM: Dehydrogenase E1 component; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; Transketolase, C-terminal domain; Biotin-requiring enzyme; Transketolase, pyrimidine binding domain; TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) synthase III; COGs: COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit; InterProIPR001017:IPR005475:IPR005476:IPR000089:IPR 013751:IPR013747; KEGG: sta:STHERM_c19760 hypothetical protein; PFAM: Tr [...]
  
  
 0.602
AEJ61083.1
TspO and MBR like protein; PFAM: TspO/MBR family; COGs: COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog); InterPro IPR004307; KEGG: sta:STHERM_c14240 hypothetical protein; PFAM: TspO/MBR-related protein; SPTR: TspO and MBR like protein.
  
    0.573
AEJ62106.1
GCN5-related N-acetyltransferase; PFAM: Acetyltransferase (GNAT) family; COGs: COG1670 Acetyltransferase including N-acetylase of ribosomal protein; InterPro IPR000182; KEGG: sta:STHERM_c17770 acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: GCN5-related N-acetyltransferase.
      0.560
AEJ61079.1
KEGG: sta:STHERM_c14280 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.543
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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