Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
AEJ61085.1KEGG: sta:STHERM_c14220 hypothetical protein; SPTR: Putative uncharacterized protein. (477 aa)    
Predicted Functional Partners:
AEJ61086.1
PFAM: Protein of unknown function (DUF1329); KEGG: sta:STHERM_c14210 hypothetical protein; SPTR: Putative uncharacterized protein.
 
     0.946
AEJ61087.1
MMPL domain protein; PFAM: MMPL family; COGs: COG1033 exporter of the RND superfamily protein; InterPro IPR004869; KEGG: sta:STHERM_c14200 transporter; PFAM: MMPL; SPTR: Putative uncharacterized protein.
 
   
 0.945
AEJ61088.1
PFAM: Bacterial regulatory proteins, tetR family; InterPro IPR001647; KEGG: sta:STHERM_c14190 hypothetical protein; PFAM: Transcriptional regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: Regulatory protein TetR.
 
     0.804
AEJ60477.1
KEGG: sta:STHERM_c02060 outer membrane protein involved in lipoprotein sorting; SPTR: Putative uncharacterized protein.
 
     0.667
AEJ60935.1
KEGG: sta:STHERM_c06410 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.649
AEJ61981.1
KEGG: sta:STHERM_c16620 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.582
AEJ61002.1
Protein of unknown function DUF2078, membrane; PFAM: Predicted membrane protein (DUF2078); InterPro IPR018649; KEGG: sta:STHERM_c14980 hypothetical protein; PFAM: Protein of unknown function DUF2078, membrane; SPTR: Putative uncharacterized protein.
  
     0.526
AEJ62543.1
KEGG: sta:STHERM_c22480 hypothetical protein; SPTR: Putative uncharacterized protein.
 
     0.525
AEJ60321.1
PFAM: Glycosyl transferases group 1; InterPro IPR001296; KEGG: sta:STHERM_c00340 hypothetical protein; PFAM: Glycosyl transferase, group 1; SPTR: Glycosyl transferase group 1.
  
     0.495
AEJ61090.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; Hpt domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR013656:IPR003661:IPR003594:IPR 001789:IPR008207; KEGG: sta:STHERM_c14170 two-component system, sensor histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS fold-4; Signal transduction response regulator, receiver region; Signal transducti [...]
  
  
 0.477
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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