STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ61088.1PFAM: Bacterial regulatory proteins, tetR family; InterPro IPR001647; KEGG: sta:STHERM_c14190 hypothetical protein; PFAM: Transcriptional regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: Regulatory protein TetR. (216 aa)    
Predicted Functional Partners:
AEJ61087.1
MMPL domain protein; PFAM: MMPL family; COGs: COG1033 exporter of the RND superfamily protein; InterPro IPR004869; KEGG: sta:STHERM_c14200 transporter; PFAM: MMPL; SPTR: Putative uncharacterized protein.
 
     0.820
AEJ61086.1
PFAM: Protein of unknown function (DUF1329); KEGG: sta:STHERM_c14210 hypothetical protein; SPTR: Putative uncharacterized protein.
 
   
 0.810
AEJ61085.1
KEGG: sta:STHERM_c14220 hypothetical protein; SPTR: Putative uncharacterized protein.
 
     0.804
AEJ61847.1
PFAM: Bacterial regulatory proteins, tetR family; InterPro IPR001647; KEGG: sta:STHERM_c15420 transcriptional regulator; PFAM: Transcriptional regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: Regulatory protein TetR.
  
     0.707
AEJ60481.1
PFAM: Bacterial regulatory proteins, tetR family; COGs: COG1309 Transcriptional regulator; InterPro IPR001647; KEGG: sta:STHERM_c02100 transcriptional activator; PFAM: Transcriptional regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: Transcriptional regulator, TetR family.
  
     0.658
AEJ61090.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; Hpt domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR013656:IPR003661:IPR003594:IPR 001789:IPR008207; KEGG: sta:STHERM_c14170 two-component system, sensor histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS fold-4; Signal transduction response regulator, receiver region; Signal transducti [...]
     
 0.547
AEJ61089.1
PFAM: Response regulator receiver domain; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: sta:STHERM_c14180 response regulator; PFAM: Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region; SPTR: Response regulator receiver protein.
     
 0.496
AEJ61084.1
PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I; COGs: COG1109 Phosphomannomutase; InterPro IPR005844; KEGG: sta:STHERM_c14230 hypothetical protein; PFAM: Alpha-D-phosphohexomutase, alpha/beta/alpha domain I; SPTR: Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I.
       0.467
AEJ62282.1
PFAM: Bacterial regulatory proteins, tetR family; InterPro IPR001647; KEGG: cpo:COPRO5265_0205 transcriptional regulator, TetR family, putative; PFAM: Transcriptional regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: Regulatory protein TetR.
  
     0.425
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.