STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ61092.1PFAM: Response regulator receiver domain; COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR001789; KEGG: sta:STHERM_c14150 hypothetical protein; PFAM: Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region; SPTR: Response regulator receiver protein. (145 aa)    
Predicted Functional Partners:
AEJ62053.1
CheA signal transduction histidine kinase; PFAM: CheW-like domain; P2 response regulator binding domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Signal transducing histidine kinase, homodimeric domain; Hpt domain; COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; InterProIPR008207:IPR003594:IPR002545:IPR010808:IPR 004105; KEGG: sta:STHERM_c17230 chemotaxis protein CheA; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, phosphotransfer (Hpt) region; Signal transduction histidine kinase, P2 response regulator-binding; Signal [...]
 
 0.970
AEJ60391.1
CheA signal transduction histidine kinase; PFAM: CheW-like domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Signal transducing histidine kinase, homodimeric domain; Hpt domain; COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; InterPro IPR008207:IPR004105:IPR003594:IPR002545; KEGG: sta:STHERM_c01160 hypothetical protein; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, phosphotransfer (Hpt) region; Signal transduction histidine kinase, subgroup, homodimeric; CheW-like protein; SMART: ATP-binding region, ATPase-like; Signal [...]
 
 0.961
AEJ61223.1
Flagellar motor switch protein FliN; FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family.
  
 0.940
AEJ60623.1
CheC, inhibitor of MCP methylation; PFAM: CheC-like family; COGs: COG1776 Chemotaxis protein CheC inhibitor of MCP methylation; InterPro IPR007597; KEGG: sta:STHERM_c03700 CheC, inhibitor of MCP methylation; PFAM: CheC-like protein; SPTR: CheC, inhibitor of MCP methylation.
 
 0.939
AEJ62051.1
CheC domain protein; PFAM: CheC-like family; COGs: COG1406 inhibitor of MCP methylation homolog of CheC; InterPro IPR007597; KEGG: sta:STHERM_c17210 chemotaxis protein CheC; PFAM: CheC-like protein; SPTR: CheC domain protein.
  
 
 0.919
AEJ60615.1
KEGG: sta:STHERM_c03610 hypothetical protein; SPTR: CheC-like family protein.
  
 
 0.905
AEJ61332.1
CheC domain protein; PFAM: CheC-like family; InterPro IPR007597; KEGG: sta:STHERM_c10340 hypothetical protein; PFAM: CheC-like protein; SPTR: CheC domain protein.
  
 
 0.905
AEJ62052.1
MCP methyltransferase, CheR-type; PFAM: CheW-like domain; CheR methyltransferase, SAM binding domain; COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR002545:IPR000780; KEGG: sta:STHERM_c17220 chemotaxis protein CheW; PFAM: MCP methyltransferase, CheR-type; CheW-like protein; SMART: CheW-like protein; MCP methyltransferase, CheR-type; SPTR: MCP methyltransferase, CheR-type.
 
 
 0.803
AEJ60863.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR001789:IPR003594; KEGG: sta:STHERM_c05630 two-component regulatory system response regulator; PFAM: Signal transduction response regulator, receiver region; ATP-binding region, ATPase-like; SMART: Signal transduction response regulator, receiver region; SPTR: Response regulator receiver sensor signal transduction histidine kinase.
 
 
 
 0.800
AEJ60380.1
PFAM: Methyl-accepting chemotaxis protein (MCP) signaling domain; COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR004089; KEGG: sta:STHERM_c01060 hypothetical protein; PFAM: Chemotaxis methyl-accepting receptor, signalling; SMART: Chemotaxis methyl-accepting receptor, signalling; SPTR: Methyl-accepting chemotaxis sensory transducer.
 
  
  0.793
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.