STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ61112.1KEGG: sta:STHERM_c13200 hypothetical protein; SPTR: Putative uncharacterized protein. (147 aa)    
Predicted Functional Partners:
AEJ61111.1
Transcriptional regulator, NifA, Fis Family; PFAM: GAF domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain; TIGRFAM: Nif-specific regulatory protein; COGs: COG3604 Transcriptional regulator containing GAF AAA-type ATPase and DNA binding domains; InterProIPR010113:IPR003018:IPR002078:IPR002197:IPR 003593; KEGG: sta:STHERM_c13210 nitrogen fixation protein AnfA; PFAM: RNA polymerase sigma factor 54, interaction; GAF; Helix-turn-helix, Fis-type; SMART: GAF; ATPase, AAA+ type, core; SPTR: DNA-binding protein Fis; TIGRFAM: Nif-specific regulatory protein.
       0.642
rpsF
30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
       0.585
AEJ61114.1
Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
       0.577
AEJ61208.1
PFAM: Flagellar hook-basal body complex protein FliE; TIGRFAM: flagellar hook-basal body complex protein FliE; COGs: COG1677 Flagellar hook-basal body protein; InterPro IPR001624; KEGG: sta:STHERM_c09090 flagellar hook-basal body complex protein FliE; PFAM: Flagellar hook-basal body complex protein FliE; SPTR: Flagellar hook-basal body complex subunit FliE; TIGRFAM: Flagellar hook-basal body complex protein FliE.
    
   0.543
AEJ62490.1
MCP methyltransferase, CheR-type; PFAM: CheR methyltransferase, SAM binding domain; CheR methyltransferase, all-alpha domain; COGs: COG1352 Methylase of chemotaxis methyl-accepting protein; InterPro IPR000780; KEGG: sta:STHERM_c21890 chemotaxis protein methyltransferase; PFAM: MCP methyltransferase, CheR-type; SMART: MCP methyltransferase, CheR-type; SPTR: MCP methyltransferase, CheR-type.
    
   0.543
rpsR
30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.
       0.532
AEJ61118.1
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.
   
   0.484
AEJ60517.1
PFAM: Methyl-accepting chemotaxis protein (MCP) signaling domain; COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR004089:IPR003660; KEGG: sta:STHERM_c02480 methyl-accepting chemotaxis protein; PFAM: Chemotaxis methyl-accepting receptor, signalling; SMART: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; SPTR: Methyl-accepting chemotaxis sensory transducer.
    
   0.454
AEJ60660.1
Methyl-accepting chemotaxis sensory transducer with Cache sensor; PFAM: Cache domain; Methyl-accepting chemotaxis protein (MCP) signaling domain; COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR003660:IPR004089:IPR004010; KEGG: sta:STHERM_c04110 methyl-accepting chemotaxis protein; PFAM: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; Cache; SMART: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; SPTR: Methyl-accepting chemotaxis sensory transducer with Cache sensor.
    
   0.454
rplI
50S ribosomal protein L9; Binds to the 23S rRNA.
       0.424
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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