STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ61123.1Undecaprenyl pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (232 aa)    
Predicted Functional Partners:
dxr
1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family.
  
  
 0.974
frr
Ribosome-recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.
 
  
 0.959
AEJ62045.1
PFAM: Polyprenyl synthetase; COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: sta:STHERM_c17140 polyprenyl synthetase; PFAM: Polyprenyl synthetase; SPTR: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
 
 
 0.953
AEJ61120.1
Membrane-associated zinc metalloprotease; PFAM: Peptidase family M50; PDZ domain (Also known as DHR or GLGF); TIGRFAM: RIP metalloprotease RseP; COGs: COG0750 membrane-associated Zn-dependent protease 1; InterPro IPR004387:IPR008915:IPR001478; KEGG: sta:STHERM_c13120 hypothetical protein; PFAM: Peptidase M50; PDZ/DHR/GLGF; SMART: PDZ/DHR/GLGF; SPTR: Membrane-associated zinc metalloprotease; TIGRFAM: Peptidase M50, putative membrane-associated zinc metallopeptidase.
 
  
 0.951
AEJ62289.1
PFAM: Polyprenyl synthetase; COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: sta:STHERM_c19820 heptaprenyl diphosphate synthase component II; PFAM: Polyprenyl synthetase; SPTR: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
 
 
 0.946
uppP
Undecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.
  
  
 0.928
AEJ60941.1
PFAM: Heptaprenyl diphosphate synthase component I; COGs: COG4769 membrane protein; InterPro IPR010898; KEGG: sta:STHERM_c06470 hypothetical protein; PFAM: Heptaprenyl diphosphate synthase component I; SPTR: Heptaprenyl diphosphate synthase component I.
     
  0.900
AEJ61122.1
PFAM: Cytidylyltransferase family; COGs: COG4589 CDP-diglyceride synthetase/phosphatidate cytidylyltransferase; InterPro IPR000374; KEGG: sta:STHERM_c13100 phosphatidate cytidylyltransferase; PFAM: Phosphatidate cytidylyltransferase; SPTR: Phosphatidate cytidylyltransferase.
 
     0.836
tsf
Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.
  
  
 0.797
nusA
NusA antitermination factor; Participates in both transcription termination and antitermination.
  
    0.751
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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