STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ61129.1Conserved hypothetical protein CHP00282; TIGRFAM: metallophosphoesterase, MG_246/BB_0505 family; COGs: COG1692 conserved hypothetical protein; InterPro IPR005235:IPR004843; KEGG: sta:STHERM_c13020 hypothetical protein; PFAM: Metallophosphoesterase; SPTR: Metallophosphoesterase; TIGRFAM: Conserved hypothetical protein CHP00282. (261 aa)    
Predicted Functional Partners:
AEJ61130.1
PFAM: FtsJ-like methyltransferase; TIGRFAM: hemolysin TlyA family protein; COGs: COG1189 rRNA methylase; InterPro IPR004538:IPR002877; KEGG: sta:STHERM_c13010 hemolysin; PFAM: Ribosomal RNA methyltransferase RrmJ/FtsJ; SPTR: Hemolysin A; TIGRFAM: Haemolysin A.
       0.811
rny
2,3 cyclic-nucleotide 2-phosphodiesterase; Endoribonuclease that initiates mRNA decay.
  
  
 0.607
folD
Bifunctional protein folD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
      0.499
tsf
Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.
 
     0.419
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.