STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
AEJ61132.1Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (577 aa)    
Predicted Functional Partners:
AEJ62498.1
Phosphotransferase system, phosphocarrier protein HPr; PFAM: PTS HPr component phosphorylation site; TIGRFAM: Phosphotransferase System HPr (HPr) Family; COGs: COG1925 Phosphotransferase system HPr-related protein; InterPro IPR005698; KEGG: sta:STHERM_c21970 phosphocarrier protein HPr; PFAM: Phosphotransferase system, phosphocarrier HPr protein; SPTR: Phosphocarrier protein HPr; TIGRFAM: Phosphotransferase system, phosphocarrier HPr protein.
 
 0.999
AEJ62536.1
Putative PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; COGs: COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); InterPro IPR002178; KEGG: sta:STHERM_c22360 hypothetical protein; PFAM: Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2; SPTR: Putative PTS IIA-like nitrogen-regulatory protein PtsN.
 
  
 0.988
AEJ62080.1
PfkB domain protein; PFAM: pfkB family carbohydrate kinase; TIGRFAM: hexose kinase, 1-phosphofructokinase family; COGs: COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); InterPro IPR011611; KEGG: sta:STHERM_c17500 sugar kinase; PFAM: Carbohydrate/purine kinase; SPTR: PfkB domain protein.
 
  
 0.860
der
GTP-binding protein engA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
     
 0.817
AEJ61135.1
KEGG: sta:STHERM_c12960 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.810
AEJ61134.1
PFAM: MerR family regulatory protein; COGs: COG0789 transcriptional regulator protein; InterPro IPR000551; KEGG: sta:STHERM_c12970 transcriptional regulatory protein; PFAM: HTH transcriptional regulator, MerR; SMART: HTH transcriptional regulator, MerR; SPTR: Transcriptional regulator, MerR family.
       0.795
AEJ60627.1
Putative PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; COGs: COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); InterPro IPR002178; KEGG: sta:STHERM_c03740 hypothetical protein; PFAM: Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2; SPTR: Putative PTS IIA-like nitrogen-regulatory protein PtsN.
 
   
 0.746
AEJ61136.1
PFAM: FliG C-terminal domain; TIGRFAM: flagellar motor switch protein FliG; COGs: COG1536 Flagellar motor switch protein; InterPro IPR000090; KEGG: sta:STHERM_c12950 flagellar motor switch protein FliG; PFAM: Flagellar motor switch protein FliG; SPTR: Flagellar motor switch protein FliG.
       0.661
AEJ61137.1
Hypothetical protein; PFAM: TM2 domain; InterPro IPR007829; KEGG: sta:STHERM_c12940 hypothetical protein; SPTR: TM2 domain-containing protein.
       0.652
AEJ61131.1
Lipoprotein LpqB, GerMN domain-containing protein; PFAM: Sporulation and spore germination; COGs: COG5401 Spore germination protein; InterPro IPR019606; KEGG: sta:STHERM_c13000 hypothetical protein; PFAM: Lipoprotein LpqB, GerMN domain; SPTR: Lipoprotein LpqB, GerMN domain.
  
    0.612
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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