STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ61175.1AAA ATPase; InterPro IPR003593; KEGG: rca:Rcas_1107 AAA ATPase; SMART: ATPase, AAA+ type, core; SPTR: AAA ATPase. (569 aa)    
Predicted Functional Partners:
AEJ61529.1
SMC domain protein; COGs: COG4637 ATPase; InterPro IPR003395; KEGG: sta:STHERM_c12270 hypothetical protein; PFAM: RecF/RecN/SMC protein, N-terminal; SPTR: SMC domain protein.
  
     0.702
AEJ61176.1
PFAM: Tetratricopeptide repeat; COGs: COG5010 Flp pilus assembly protein TadD contains TPR repeats; InterPro IPR001440:IPR011717:IPR013105:IPR019734; KEGG: sta:STHERM_c08780 hypothetical protein; PFAM: Tetratricopeptide TPR-1; Tetratricopeptide TPR-4; Tetratricopeptide TPR2; SMART: Tetratricopeptide repeat; SPTR: Tetratricopeptide TPR_1 repeat-containing protein.
       0.603
AEJ61174.1
KEGG: sta:STHERM_c08770 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.494
cas2-2
CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
  
     0.491
AEJ61886.1
PFAM: HEPN domain; InterPro IPR007842; KEGG: sta:STHERM_c15560 hypothetical protein; PFAM: HEPN; SPTR: HEPN domain protein.
  
     0.476
AEJ60974.1
CRISPR-associated protein Cas4; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family.
  
     0.461
AEJ61818.1
DNA polymerase beta domain protein region; PFAM: Nucleotidyltransferase domain; InterPro IPR002934; KEGG: sta:STHERM_c15240 hypothetical protein; PFAM: Nucleotidyltransferase; SPTR: DNA polymerase beta domain protein region.
 
     0.452
AEJ61817.1
PFAM: HEPN domain; COGs: COG2250 conserved hypothetical protein related to C-terminal domain of eukaryotic chaperone SACSIN; InterPro IPR007842; KEGG: rca:Rcas_0705 HEPN domain-containing protein; PFAM: HEPN; SMART: HEPN; SPTR: HEPN domain protein.
  
     0.439
AEJ60980.1
PFAM: Uncharacterized conserved protein (DUF2276); KEGG: atm:ANT_28420 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.430
AEJ61865.1
DNA polymerase subunit beta; PFAM: Nucleotidyltransferase domain; KEGG: rca:Rcas_3922 DNA polymerase subunit beta; SPTR: DNA polymerase beta subunit.
 
   
 0.427
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.