Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEJ61186.1KEGG: sta:STHERM_c08870 hypothetical protein; SPTR: Putative uncharacterized protein. (278 aa)    
Predicted Functional Partners:
AEJ61187.1
Methyltransferase type 11; PFAM: Methyltransferase domain; COGs: COG2227 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1 4-benzoquinol methylase; InterPro IPR013216; KEGG: sta:STHERM_c08880 methyltransferase; PFAM: Methyltransferase type 11; SPTR: Methyltransferase type 11.
   
   0.807
AEJ61185.1
KEGG: sta:STHERM_c08860 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.773
AEJ61188.1
KEGG: sta:STHERM_c08890 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.680
AEJ61189.1
PFAM: Domain of unknown function (DUF1957); Glycosyl hydrolase family 57; COGs: COG1543 conserved hypothetical protein; InterPro IPR004300:IPR013202:IPR015293; KEGG: sta:STHERM_c08900 hypothetical protein; PFAM: Domain of unknown function DUF1957; Glycoside hydrolase, family 57, core; Kinin peptide, insect; SPTR: (1->4)-alpha-D-glucan branching enzyme.
       0.680
AEJ61262.1
Cell wall hydrolase/autolysin; PFAM: N-acetylmuramoyl-L-alanine amidase; COGs: COG0860 N-acetylmuramoyl-L-alanine amidase; InterPro IPR002508; KEGG: sta:STHERM_c09650 hypothetical protein; PFAM: Cell wall hydrolase/autolysin, catalytic; SMART: Cell wall hydrolase/autolysin, catalytic; SPTR: Cell wall hydrolase/autolysin.
   
 
 0.675
AEJ61184.1
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
       0.563
AEJ60956.1
Tetratricopeptide TPR_2 repeat-containing protein; PFAM: Tetratricopeptide repeat; InterPro IPR001440:IPR013105:IPR019734; KEGG: sta:STHERM_c06620 TPR domain-containing protein; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; SPTR: Tetratricopeptide TPR_1 repeat-containing protein.
  
 
 0.457
AEJ62432.1
Tetratricopeptide TPR_1 repeat-containing protein; PFAM: Tetratricopeptide repeat; InterPro IPR001440:IPR013105:IPR019734; KEGG: sta:STHERM_c21310 hypothetical protein; PFAM: Tetratricopeptide TPR-1; Tetratricopeptide TPR2; SPTR: Tetratricopeptide TPR_1 repeat-containing protein.
  
 
 0.457
AEJ61195.1
PFAM: Cell cycle protein; TIGRFAM: cell division protein FtsW; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182:IPR013437; KEGG: sta:STHERM_c08960 hypothetical protein; PFAM: Cell cycle protein; SPTR: Cell division protein FtsW; TIGRFAM: Cell division protein FtsW; Belongs to the SEDS family.
     
 0.420
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
    0.417
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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