Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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AEJ61187.1Methyltransferase type 11; PFAM: Methyltransferase domain; COGs: COG2227 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1 4-benzoquinol methylase; InterPro IPR013216; KEGG: sta:STHERM_c08880 methyltransferase; PFAM: Methyltransferase type 11; SPTR: Methyltransferase type 11. (284 aa)    
Predicted Functional Partners:
AEJ61186.1
KEGG: sta:STHERM_c08870 hypothetical protein; SPTR: Putative uncharacterized protein.
   
   0.807
AEJ61185.1
KEGG: sta:STHERM_c08860 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.762
AEJ61189.1
PFAM: Domain of unknown function (DUF1957); Glycosyl hydrolase family 57; COGs: COG1543 conserved hypothetical protein; InterPro IPR004300:IPR013202:IPR015293; KEGG: sta:STHERM_c08900 hypothetical protein; PFAM: Domain of unknown function DUF1957; Glycoside hydrolase, family 57, core; Kinin peptide, insect; SPTR: (1->4)-alpha-D-glucan branching enzyme.
     
 0.722
AEJ61188.1
KEGG: sta:STHERM_c08890 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.695
AEJ61184.1
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
       0.547
AEJ61261.1
ATP-grasp fold domain protein, DUF201-type; PFAM: ATP-grasp domain; COGs: COG0439 Biotin carboxylase; InterPro IPR003806; KEGG: sta:STHERM_c09640 CarB family protein; PFAM: ATP-grasp fold, DUF201-type; SPTR: Putative uncharacterized protein.
 
  
 0.523
AEJ61200.1
Tetratricopeptide TPR_1 repeat-containing protein; PFAM: Tetratricopeptide repeat; InterPro IPR001440:IPR019734; KEGG: sta:STHERM_c09010 TPR domain-containing protein; PFAM: Tetratricopeptide TPR-1; SMART: Tetratricopeptide repeat; SPTR: Tetratricopeptide TPR_1 repeat-containing protein.
 
     0.509
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
   
 0.508
AEJ61208.1
PFAM: Flagellar hook-basal body complex protein FliE; TIGRFAM: flagellar hook-basal body complex protein FliE; COGs: COG1677 Flagellar hook-basal body protein; InterPro IPR001624; KEGG: sta:STHERM_c09090 flagellar hook-basal body complex protein FliE; PFAM: Flagellar hook-basal body complex protein FliE; SPTR: Flagellar hook-basal body complex subunit FliE; TIGRFAM: Flagellar hook-basal body complex protein FliE.
 
     0.501
AEJ61214.1
KEGG: sta:STHERM_c09150 hypothetical protein; SPTR: Putative uncharacterized protein.
 
 
   0.476
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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