STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ61232.1KEGG: sta:STHERM_c09330 hypothetical protein; SPTR: Putative uncharacterized protein. (206 aa)    
Predicted Functional Partners:
AEJ61233.1
RNA polymerase, sigma 28 subunit, FliA/WhiG; PFAM: Sigma-70, region 4; Sigma-70 region 3; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, FliA/WhiG family; RNA polymerase sigma factor, sigma-70 family; COGs: COG1191 DNA-directed RNA polymerase specialized sigma subunit; InterProIPR007627:IPR007624:IPR007630:IPR014284:IPR 012845; KEGG: sta:STHERM_c09340 hypothetical protein; PFAM: RNA polymerase sigma-70 region 4; RNA polymerase sigma-70 region 2; RNA polymerase sigma-70 region 3; SPTR: RNA polymerase sigma factor; TIGRFAM: RNA polymerase sigma factor, FliA/WhiG; RNA polymerase [...]
       0.773
AEJ61234.1
PFAM: Protein of unknown function (DUF342); COGs: COG1315 polymerase most protein contain PALM domain HD hydrolase domain and Zn-ribbon domain; InterPro IPR005646; KEGG: sta:STHERM_c09350 polymerase most proteins contain PALM domain HD hydrolase domain and Zn-ribbon domain; PFAM: Protein of unknown function DUF342; SPTR: Putative uncharacterized protein.
       0.768
AEJ61235.1
KEGG: sta:STHERM_c09360 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.768
AEJ61236.1
KEGG: sta:STHERM_c09370 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.762
AEJ61230.1
PFAM: SRP54-type protein, GTPase domain; TIGRFAM: flagellar biosynthetic protein FlhF; COGs: COG1419 Flagellar GTP-binding protein; InterPro IPR000897:IPR020006:IPR003593; KEGG: sta:STHERM_c09310 flagellar-associated GTP-binding protein; PFAM: Signal recognition particle, SRP54 subunit, GTPase; SMART: ATPase, AAA+ type, core; SPTR: Flagellar-associated GTP-binding protein; TIGRFAM: Signal-recognition particle (SRP)-type GTPase.
       0.532
AEJ61231.1
Cobyrinic acid ac-diamide synthase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; COGs: COG0455 ATPase involved in chromosome partitioning; InterPro IPR002586; KEGG: sta:STHERM_c09320 flagellar synthesis regulator FleN; PFAM: Cobyrinic acid a,c-diamide synthase; SPTR: Flagellar synthesis regulator FleN.
       0.532
flhA
Flagellar biosynthesis protein FlhA; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
       0.503
AEJ61227.1
Flagellar biosynthetic protein FliR; Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family.
       0.488
flhB
Flagellar biosynthetic protein FlhB; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the type III secretion exporter family.
       0.488
fliQ
Flagellar biosynthetic protein FliQ; Role in flagellar biosynthesis. Belongs to the FliQ/MopD/SpaQ family.
       0.473
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.