Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEJ61234.1PFAM: Protein of unknown function (DUF342); COGs: COG1315 polymerase most protein contain PALM domain HD hydrolase domain and Zn-ribbon domain; InterPro IPR005646; KEGG: sta:STHERM_c09350 polymerase most proteins contain PALM domain HD hydrolase domain and Zn-ribbon domain; PFAM: Protein of unknown function DUF342; SPTR: Putative uncharacterized protein. (647 aa)    
Predicted Functional Partners:
AEJ61233.1
RNA polymerase, sigma 28 subunit, FliA/WhiG; PFAM: Sigma-70, region 4; Sigma-70 region 3; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, FliA/WhiG family; RNA polymerase sigma factor, sigma-70 family; COGs: COG1191 DNA-directed RNA polymerase specialized sigma subunit; InterProIPR007627:IPR007624:IPR007630:IPR014284:IPR 012845; KEGG: sta:STHERM_c09340 hypothetical protein; PFAM: RNA polymerase sigma-70 region 4; RNA polymerase sigma-70 region 2; RNA polymerase sigma-70 region 3; SPTR: RNA polymerase sigma factor; TIGRFAM: RNA polymerase sigma factor, FliA/WhiG; RNA polymerase [...]
 
     0.854
AEJ61222.1
Flagellar motor switch protein FliM; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
 
     0.831
AEJ61236.1
KEGG: sta:STHERM_c09370 hypothetical protein; SPTR: Putative uncharacterized protein.
     
 0.828
AEJ61211.1
PFAM: Flagellar assembly protein FliH; COGs: COG1317 Flagellar biosynthesis/type III secretory pathway protein; InterPro IPR018035; KEGG: sta:STHERM_c09120 flagellar assembly protein; PFAM: Flagellar assembly protein FliH/Type III secretion system HrpE; SPTR: Flagellar assembly protein FliH/Type III secretion system HrpE.
 
     0.825
AEJ61218.1
PFAM: Flagellar protein (FlbD); COGs: COG1582 Uncharacterized protein possibly involved in motility; InterPro IPR009384; KEGG: sta:STHERM_c09190 flagellar protein; PFAM: Flagellar; SPTR: Flagellar protein.
 
   
 0.805
AEJ61235.1
KEGG: sta:STHERM_c09360 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.805
AEJ61221.1
Flagellar basal body-associated protein FliL; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.
 
     0.791
AEJ61231.1
Cobyrinic acid ac-diamide synthase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; COGs: COG0455 ATPase involved in chromosome partitioning; InterPro IPR002586; KEGG: sta:STHERM_c09320 flagellar synthesis regulator FleN; PFAM: Cobyrinic acid a,c-diamide synthase; SPTR: Flagellar synthesis regulator FleN.
 
     0.784
AEJ61232.1
KEGG: sta:STHERM_c09330 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.768
AEJ61208.1
PFAM: Flagellar hook-basal body complex protein FliE; TIGRFAM: flagellar hook-basal body complex protein FliE; COGs: COG1677 Flagellar hook-basal body protein; InterPro IPR001624; KEGG: sta:STHERM_c09090 flagellar hook-basal body complex protein FliE; PFAM: Flagellar hook-basal body complex protein FliE; SPTR: Flagellar hook-basal body complex subunit FliE; TIGRFAM: Flagellar hook-basal body complex protein FliE.
 
     0.761
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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