STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEJ61240.1Hypothetical protein; COGs: COG0857 BioD-like N-terminal domain of phosphotransacetylase; KEGG: sta:STHERM_c09410 hypothetical protein; SPTR: Putative uncharacterized protein. (387 aa)    
Predicted Functional Partners:
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
  
  
 0.918
AEJ61241.1
PFAM: LeuA allosteric (dimerisation) domain; HMGL-like; TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterPro IPR000891:IPR013709:IPR005675; KEGG: sta:STHERM_c09420 AIPM/Hcit synthase family transferase; PFAM: Pyruvate carboxyltransferase; 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain; SPTR: (R)-citramalate synthase; TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase related; Belongs to the alpha-IPM synthase/homocitrate synthase family.
       0.773
AEJ61242.1
MULE transposase, conserved domain-containing protein; PFAM: Transposase, Mutator family; COGs: COG3328 Transposase and inactivated derivatives; InterPro IPR018289; KEGG: sta:STHERM_c00050 transposase for insertion sequence element ISRM5; PFAM: MULE transposase, conserved domain; SPTR: MULE transposase, conserved domain.
       0.773
AEJ61237.1
KEGG: sta:STHERM_c09380 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.615
AEJ61238.1
PFAM: Biopolymer transport protein ExbD/TolR; COGs: COG0848 Biopolymer transport protein; InterPro IPR003400; KEGG: sta:STHERM_c09390 hypothetical protein; PFAM: Biopolymer transport protein ExbD/TolR; SPTR: Putative uncharacterized protein.
       0.615
AEJ61239.1
PFAM: MotA/TolQ/ExbB proton channel family; COGs: COG0811 Biopolymer transport protein; InterPro IPR002898; KEGG: sta:STHERM_c09400 TolQ-type transport protein; PFAM: MotA/TolQ/ExbB proton channel; SPTR: MotA/TolQ/ExbB proton channel.
       0.615
AEJ61982.1
PFAM: domain; Domain of unknown function; Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895:IPR002880:IPR019752:IPR019456:IPR 001450:IPR011766; KEGG: sta:STHERM_c16630 pyruvate-flavodoxin oxidoreductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin ox [...]
     
 0.530
AEJ60343.1
KEGG: sta:STHERM_c00560 hypothetical protein; SPTR: Putative uncharacterized protein.
 
     0.403
Your Current Organism:
Spirochaeta thermophila
NCBI taxonomy Id: 869211
Other names: S. thermophila DSM 6578, Spirochaeta thermophila DSM 6578, Spirochaeta thermophila str. DSM 6578, Spirochaeta thermophila strain DSM 6578
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